Most adaption processes have a polygenic genetic basis, but even with the recent explosive
growth of genomic data we are still lacking a unified framework describing the dynamics of …

The analysis of polymorphism data is becoming increasingly important as a complementary
tool to classical genetic analyses. Nevertheless, despite plunging sequencing costs …

Drosophila melanogaster is a valuable invertebrate model for viral infection and antiviral
immunity, and is a focus for studies of insect-virus coevolution. Here we use a metagenomic …

Evolve and resequence (E&R) experiments use experimental evolution to adapt populations
to a novel environment, then next-generation sequencing to analyse genetic changes. They …

Developmental plasticity refers to the property by which the same genotype produces
distinct phenotypes depending on the environmental conditions under which development …

Evolve and resequence (E&R) is a new approach to investigate the genomic responses to
selection during experimental evolution. By using whole genome sequencing of pools of …

Immune cells provide defense against non‐self and have recently been shown to also play
key roles in diverse processes such as development, metabolism, and tumor progression …

Population genetics largely rests on a 'standard model'in which random genetic drift is the
dominant force, selective sweeps occur infrequently, and deleterious mutations are purged …

Wolbachia is a maternally transmitted bacterium that lives inside arthropod cells. Historically,
it was viewed primarily as a parasite that manipulates host reproduction, but more recently it …

The sexes show profound differences in responses to infection and the development of
autoimmunity. Dimorphisms in immune responses are ubiquitous across taxa, from …