The role of Src kinase in macrophage‐mediated inflammatory responses
SE Byeon, YS Yi, J Oh, BC Yoo, S Hong… - Mediators of …, 2012 - Wiley Online Library
Src kinase (Src) is a tyrosine protein kinase that regulates cellular metabolism, survival, and
proliferation. Many studies have shown that Src plays multiple roles in macrophage …
proliferation. Many studies have shown that Src plays multiple roles in macrophage …
dsRNA-activation of TLR3 and RLR signaling: gene induction-dependent and independent effects
S Chattopadhyay, GC Sen - Journal of interferon & cytokine …, 2014 - liebertpub.com
Double-stranded (ds) RNA has diverse roles in host defense and disease prevention.
dsRNA, produced by viral replication, elicits strong antiviral responses in host; similar …
dsRNA, produced by viral replication, elicits strong antiviral responses in host; similar …
Toll‐like receptor 3 in viral pathogenesis: friend or foe?
R Perales‐Linares, S Navas‐Martin - Immunology, 2013 - Wiley Online Library
Viral infections frequently induce acute and chronic inflammatory diseases, yet the
contribution of the innate immune response to a detrimental host response remains poorly …
contribution of the innate immune response to a detrimental host response remains poorly …
GATA-3 regulates the self-renewal of long-term hematopoietic stem cells
C Frelin, R Herrington, S Janmohamed, M Barbara… - Nature …, 2013 - nature.com
The transcription factor GATA-3 is expressed and required for differentiation and function
throughout the T lymphocyte lineage. Despite evidence it may also be expressed in …
throughout the T lymphocyte lineage. Despite evidence it may also be expressed in …
Extracellular HSP27 mediates angiogenesis through Toll‐like receptor 3
The heat‐shock protein 27 (HSP27) is up‐regulated in tumor cells and released in their
microenvironment. Here, we show that extracellular HSP27 has a proangiogenic effect …
microenvironment. Here, we show that extracellular HSP27 has a proangiogenic effect …
Tyrosine phosphorylation in Toll-like receptor signaling
S Chattopadhyay, GC Sen - Cytokine & growth factor reviews, 2014 - Elsevier
There is a wealth of knowledge about how different Ser/Thr protein kinases participate in
Toll-like receptor (TLR) signaling. In many cases, we know the identities of the Ser/Thr …
Toll-like receptor (TLR) signaling. In many cases, we know the identities of the Ser/Thr …
TLR3-activated monocyte-derived dendritic cells trigger progression from acute viral infection to chronic disease in the lung
Acute infection is implicated as a trigger for chronic inflammatory disease, but the full basis
for this switch is uncertain. In this study, we examine this issue using a mouse model of …
for this switch is uncertain. In this study, we examine this issue using a mouse model of …
RNA-induced inflammation and migration of precursor neurons initiates neuronal circuit regeneration in zebrafish
C Vandestadt, GC Vanwalleghem, MA Khabooshan… - Developmental cell, 2021 - cell.com
Tissue regeneration and functional restoration after injury are considered as stem-and
progenitor-cell-driven processes. In the central nervous system, stem cell-driven repair is …
progenitor-cell-driven processes. In the central nervous system, stem cell-driven repair is …
When innate immunity meets angiogenesis—the role of toll-like receptors in endothelial cells and pulmonary hypertension
Toll-like receptors serve a central role in innate immunity, but they can also modulate cell
function in various non-immune cell types including endothelial cells. Endothelial cells are …
function in various non-immune cell types including endothelial cells. Endothelial cells are …
Dengue virus infection increases microglial cell migration
MK Jhan, TT Tsai, CL Chen, CC Tsai, YL Cheng… - Scientific reports, 2017 - nature.com
Activated microglial cells are present in dengue virus (DENV)-infected brains; however, the
possible effects of DENV on microglia remain unclear. Here, we demonstrated DENV …
possible effects of DENV on microglia remain unclear. Here, we demonstrated DENV …