Roles of interfacial water states on advanced biomedical material design

K Nishida, T Anada, M Tanaka - Advanced Drug Delivery Reviews, 2022 - Elsevier
When biomedical materials come into contact with body fluids, the first reaction that occurs
on the material surface is hydration; proteins are then adsorbed and denatured on the …

Role of interfacial water in determining the interactions of proteins and cells with hydrated materials

M Tanaka, S Morita, T Hayashi - Colloids and Surfaces B: Biointerfaces, 2021 - Elsevier
Water molecules play a crucial role in biointerfacial interactions, including protein adsorption
and desorption. To understand the role of water in the interaction of proteins and cells at …

Fluorine-containing bio-inert polymers: Roles of intermediate water

R Koguchi, K Jankova, M Tanaka - Acta Biomaterialia, 2022 - Elsevier
Fluorine-containing polymers are used not only in industrial processes but also in medical
applications, because they exhibit excellent heat, weather, and chemical resistance. As …

Design of biomaterials through direct ring-opening metathesis polymerisation of functionalised cyclic alkenes

S Kobayashi, M Tanaka - Molecular Systems Design & Engineering, 2023 - pubs.rsc.org
Ring-opening metathesis polymerisation (ROMP) has become a popular method for
synthesising complex functional polymers owing to the high functional group tolerance of …

The intermediate water concept for pioneering polymeric biomaterials: A review and update

S Nishimura, M Tanaka - Bulletin of the Chemical Society of …, 2023 - academic.oup.com
Polymeric biomaterials are often used in water and hydration water molecules with different
mobilities, such as non-freezing water, intermediate water, and free water, are formed on …

[HTML][HTML] Sulfonated PAM/PPy cryogels with lowered evaporation enthalpy for highly efficient photothermal water evaporation

SC Hou, DW Zhang, J Chen, XX Guo, A Haleem… - Polymers, 2023 - mdpi.com
Because of the increasing scarcity of water resources, the desalination of seawater by
photothermal evaporation with harvested solar energy has gradually become a popular …

Effects of side-chain spacing and length on hydration states of poly (2-methoxyethyl acrylate) analogues: A molecular dynamics study

AT Kuo, S Urata, R Koguchi, T Sonoda… - ACS Biomaterials …, 2021 - ACS Publications
Hydration states of polymers are known to directly influence the adsorption of biomolecules.
Particularly, intermediate water (IW) has been found able to prevent protein adsorption …

Revealing the hidden dynamics of confined water in acrylate polymers: Insights from hydrogen-bond lifetime analysis

K Shikata, T Kikutsuji, N Yasoshima, K Kim… - The Journal of …, 2023 - pubs.aip.org
Polymers contain functional groups that participate in hydrogen bond (H-bond) with water
molecules, establishing a robust H-bond network that influences bulk properties. This study …

Molecular structure and vibrational spectra of water molecules sorbed in poly (2-methoxyethylacrylate) revealed by molecular dynamics simulation

N Yasoshima, T Ishiyama, M Gemmei-Ide… - The Journal of …, 2021 - ACS Publications
Molecular dynamics (MD) simulations of water sorption in poly (2-methoxyethylacrylate)(
PMEA) are carried out to elucidate the hydrogen bonding (H-bonding) structures of the water …

Molecular dynamics study on the water mobility and side-chain flexibility of hydrated poly (ω-methoxyalkyl acrylate) s

AT Kuo, S Urata, R Koguchi, T Sonoda… - ACS Biomaterials …, 2020 - ACS Publications
Intermediate water (IW) is known to play an important role in the antifouling property of
biocompatible polymers. However, how IW prevents protein adsorption is still unclear. To …