Functional status is considered the main determinant of healthy aging. Impairment in
skeletal muscle and the cardiovascular system, two interrelated systems, results in …

Several benefits can be acquired through physical exercise. Different classes of
biomolecules are responsible for the cross-talk between distant organs. The secretome of …

Obesity is strongly related to leptin resistance that refers to the state in which leptin fails to
inhibit appetite, enhance energy expenditure and regulate glycolipid metabolism, whereas …

Simple Summary Adipose tissue secretes bioactive substances called adipokines that affect
cardiometabolic health. High-intensity interval training has a beneficial effect on …

Nicotinamide phosphoribosyltransferase (NAMPT) plays a central role in mammalian cell
metabolism by contributing to nicotinamide adenine dinucleotide biosynthesis. However …

The prevalence of obesity in the pediatric population has become a major public health
issue. Indeed, the dramatic increase of this epidemic causes multiple and harmful …

Background: This study aimed to evaluate the effects of a combination of aerobic-resistance
training (CARET) and broccoli supplementation on dectin-1 levels and insulin resistance in …

Background Neuregulin 4 (Nrg4) is an adipokine that is sensitive to energy expenditure and
with a potential role in metabolic homeostasis and obesity. This study examined the effects …

Human adipocytes release multiple adipokines into the bloodstream during physical activity.
This affects many organs and might contribute to the induction of inflammation. In this study …

Regular physical activity and the use of nutritional supplements, including antioxidants, are
recognized as efficacious approaches for the prevention and mitigation of obesity-related …