[PDF][PDF] Prostaglandin pathways: opportunities for cancer prevention and therapy

Q Wang, RJ Morris, AM Bode, T Zhang - Cancer research, 2022 - AACR
Because of profound effects observed in carcinogenesis, prostaglandins (PGs),
prostaglandin-endoperoxide synthases, and PG receptors are implicated in cancer …

EP2 antagonists (2011–2021): a decade's journey from discovery to therapeutics

MN Sluter, R Hou, L Li, N Yasmen, Y Yu… - Journal of medicinal …, 2021 - ACS Publications
In the wake of health disasters associated with the chronic use of cyclooxygenase-2 (COX-2)
inhibitor drugs, it has been widely proposed that modulation of downstream prostanoid …

[HTML][HTML] Prostaglandin E2 in neuroblastoma: Targeting synthesis or signaling?

R Hou, Y Yu, J Jiang - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Neuroblastoma (NB) is the most common pediatric extracranial solid tumor arising from
neural crest cells of the developing sympathetic nervous system. Despite marked advances …