The investigation of macromolecular biomolecules with ion mobility mass spectrometry (IM-
MS) techniques has provided substantial insights into the field of structural biology over the …

Extracellular vesicles (EVs), including microvesicles and exosomes, are nano-to micron-
sized vesicles, which may deliver bioactive cargos that include lipids, growth factors and …

Background Extracellular vesicles (EV), the collective term for vesicles released from cells,
consist of vesicle species ranging in size from 30 nm to 5 µm in diameter. These vesicles are …

The protein refractive index increment, dn/dc, is an important parameter underlying the
concentration determination and the biophysical characterization of proteins and protein …

Extracellular vesicles (EVs) are cell-derived vesicles present in body fluids that play an
essential role in various cellular processes, such as intercellular communication …

Analytical ultracentrifugation (AUC) is a versatile and powerful method for the quantitative
analysis of macromolecules in solution. AUC has broad applications for the study of …

Microvesicles are nano-sized lipid vesicles released by all cells in vivo and in vitro. They are
released physiologically under normal conditions but their rate of release is higher under …

Modern computational strategies have allowed for the direct modeling of the sedimentation
process of heterogeneous mixtures, resulting in sedimentation velocity (SV) size‐distribution …

Transcription in eukaryotic genomes depends on enzymes that regulate the degree of
histone H3 lysine 4 (H3K4) methylation. The mixed lineage leukemia protein-1 (MLL1) is a …

After briefly introducing the theoretical equations for DLS based particle size analysis, the
need for angular dependent DLS investigations is emphasized to obtain correct particle …