Chronic pain is a maladaptive neurological disease that remains a major health problem. A
deepening of our knowledge on mechanisms that cause pain is a prerequisite to developing …

Diabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus that
affects approximately half of patients with diabetes. Current treatment regimens cannot treat …

Aging is associated with increased prevalence of axonal injuries characterized by poor
regeneration and disability. However, the underlying mechanisms remain unclear. In our …

Fibromyalgia is a debilitating widespread chronic pain syndrome that occurs in 2 to 4% of
the population. The prevailing view that fibromyalgia results from central nervous system …

The immune system is critically involved in the development and maintenance of chronic
pain. However, T cells, one of the main regulators of the immune response, have only …

Diabetic peripheral neuropathy (DPN) is one of the most common complications of diabetes
mellitus (DM) and affects over one-third of all patients. Neuropathic pain and nerve …

Endometriosis, a debilitating condition, affects one in ten women of reproductive age. Its
pathophysiology remains unclear, though deficiencies in immune surveillance are thought to …

Diabetic peripheral neuropathy (DPN) is one of the most common chronic complications in
diabetes. Previous studies have shown that chronic neuroinflammation was associated with …

Background Diabetic peripheral neuropathy (DPN) constitutes a debilitating complication
associated with diabetes. Although, the past decade has seen rapid developments in …

Chronic pain is a common symptom of most clinical diseases, which seriously affects the
psychosomatic health of patients and brings some pain to patients. Due to its pathological …