To analyse published evidence on the economic evaluation of risk‐based screening (RBS),
a full systematic literature review was conducted. After a quality appraisal, we compared the …

Importance Head and neck cancers (HNCs) are often diagnosed at advanced clinical stages
during their symptomatic phase, leading to a reduced treatment window and poor survival …

The stroma in solid tumors severely impedes drug delivery via systemic administration to
cancer cells, especially when using nano-drug delivery systems. Therefore, we developed …

Background The effectiveness of sacituzumab govitecan for metastatic triple-negative breast
cancer (TNBC) has been reported in recent research, however, the value of the …

Importance Primary care physicians (PCPs) are significant contributors of early cancer
detection, yet few studies have investigated whether consistent primary care translates to …

Background: Breast cancer screening in Ontario, Canada, was deferred during the first wave
of the COVID-19 pandemic, and a prioritization framework to resume services according to …

Simple Summary For women who have tested positive for BRCA mutations, the decision to
make use of preventive surgical options, such as risk-reducing mastectomy (RRM) or risk …

Acute myeloid leukemia (AML) is the most common acute leukemia in adults in the United
States and has seen the approval of several novel agents over the past decade. Similar to …

Background Although several studies from Europe and the US have shown promising
screening results favoring digital breast tomosynthesis compared with standard digital …

Executive summary The Lancet Breast Cancer Commission—a diverse, multidisciplinary
international group—are unanimous in our determination to improve the lives of all people …