Background Different pharmacological approaches aimed at opioid detoxification are
effective. Nevertheless a majority of patients relapse to heroin use, and relapses are a …

The diversion, misuse, and non-medically supervised use of buprenorphine and
buprenorphine/naloxone by opioid users are reviewed. Buprenorphine and buprenorphine …

These Guidelinesreview the use of medicines such as methadone, buprenorphine,
naltrexone and clonidine in combination with psychosocial support in the treatment of …

Aims To (i) examine the predictors of mortality in a randomized study of methadone versus
buprenorphine maintenance treatment;(ii) compare the survival experience of the …

Objective To advise physicians on which treatment options to recommend for specific patient
populations: abstinence-based treatment, buprenorphine-naloxone maintenance, or …

Background Managed withdrawal is a necessary step prior to drug‐free treatment or as the
endpoint of substitution treatment. Objectives To assess the effects of buprenorphine versus …

Buprenorphine is an effective long-term opioid agonist treatment. As the only
pharmacological treatment for opioid dependence readily available in office-based settings …

This was a 6-month, randomized, flexible-dose study comparing the effects of methadone
(Meth) and buprenorphine (Bup) on retention rate and substance use in a sample of 140 …

Opioid use disorder (OUD) is a common, treatable chronic disease that can be effectively
managed in primary care settings. Untreated OUD is associated with considerable morbidity …

BACKGROUND: Buprenorphine/naloxone was approved by the FDA for office-based opioid
maintenance therapy (OMT), with little long-term follow-up data from actual office-based …