[HTML][HTML] Beyond diversity loss and climate change: Impacts of Amazon deforestation on infectious diseases and public health

JH Ellwanger, B Kulmann-Leal, VL Kaminski… - Anais da Academia …, 2020 - SciELO Brasil
Amazonian biodiversity is increasingly threatened due to the weakening of policies for
combating deforestation, especially in Brazil. Loss of animal and plant species, many not yet …

Approved antiviral drugs over the past 50 years

E De Clercq, G Li - Clinical microbiology reviews, 2016 - Am Soc Microbiol
Since the first antiviral drug, idoxuridine, was approved in 1963, 90 antiviral drugs
categorized into 13 functional groups have been formally approved for the treatment of the …

Evolution and epidemic spread of SARS-CoV-2 in Brazil

DS Candido, IM Claro, JG De Jesus, WM Souza… - Science, 2020 - science.org
Brazil currently has one of the fastest-growing severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) epidemics in the world. Because of limited available data …

A species-level timeline of mammal evolution integrating phylogenomic data

S Álvarez-Carretero, AU Tamuri, M Battini… - Nature, 2022 - nature.com
High-throughput sequencing projects generate genome-scale sequence data for species-
level phylogenies,–. However, state-of-the-art Bayesian methods for inferring timetrees are …

Zoonotic spillover: Understanding basic aspects for better prevention

JH Ellwanger, JAB Chies - Genetics and Molecular Biology, 2021 - SciELO Brasil
The transmission of pathogens from wild animals to humans is called “zoonotic spillover”.
Most human infectious diseases (60-75%) are derived from pathogens that originally …

HIV subtype diversity worldwide

N Bbosa, P Kaleebu, D Ssemwanga - Current Opinion in HIV and …, 2019 - journals.lww.com
The dynamic change in HIV subtype distribution presents future challenges for diagnosis,
treatment and vaccine design and development. An increase in recombinant viruses …

Global and regional molecular epidemiology of HIV-1, 1990–2015: a systematic review, global survey, and trend analysis

J Hemelaar, R Elangovan, J Yun… - The Lancet infectious …, 2019 - thelancet.com
Background Global genetic diversity of HIV-1 is a major challenge to the development of HIV
vaccines. We aimed to estimate the regional and global distribution of HIV-1 subtypes and …

Modeling infectious disease dynamics in the complex landscape of global health

H Heesterbeek, RM Anderson, V Andreasen, S Bansal… - Science, 2015 - science.org
BACKGROUND Despite many notable successes in prevention and control, infectious
diseases remain an enormous threat to human and animal health. The ecological and …

Timing the SARS-CoV-2 index case in Hubei province

J Pekar, M Worobey, N Moshiri, K Scheffler… - Science, 2021 - science.org
Understanding when severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
emerged is critical to evaluating our current approach to monitoring novel zoonotic …

HIV persists throughout deep tissues with repopulation from multiple anatomical sources

A Chaillon, S Gianella, S Dellicour… - The Journal of …, 2020 - Am Soc Clin Investig
BACKGROUND Understanding HIV dynamics across the human body is important for cure
efforts. This goal has been hampered by technical difficulties and the challenge of obtaining …