Microfluidic paper-based analytical devices: from design to applications

E Noviana, T Ozer, CS Carrell, JS Link… - Chemical …, 2021 - ACS Publications
Microfluidic paper-based analytical devices (μPADs) have garnered significant interest as a
promising analytical platform in the past decade. Compared with traditional microfluidics …

Turning the page: advancing paper-based microfluidics for broad diagnostic application

MM Gong, D Sinton - Chemical reviews, 2017 - ACS Publications
Infectious diseases are a major global health issue. Diagnosis is a critical first step in
effectively managing their spread. Paper-based microfluidic diagnostics first emerged in …

Point-of-care diagnostics: recent developments in a connected age

S Nayak, NR Blumenfeld, T Laksanasopin… - Analytical …, 2017 - ACS Publications
The field of point-of-care (POC) diagnostics offers the tantalizing possibility of providing
rapid diagnostic results in nonlaboratory settings. Here, we review progress in this research …

Advances in point-of-care nucleic acid extraction technologies for rapid diagnosis of human and plant diseases

R Paul, E Ostermann, Q Wei - Biosensors and bioelectronics, 2020 - Elsevier
Global health and food security constantly face the challenge of emerging human and plant
diseases caused by bacteria, viruses, fungi, and other pathogens. Disease outbreaks such …

Microfluidics-based strategies for molecular diagnostics of infectious diseases

X Wang, XZ Hong, YW Li, Y Li, J Wang, P Chen… - Military Medical …, 2022 - Springer
Traditional diagnostic strategies for infectious disease detection require benchtop
instruments that are inappropriate for point-of-care testing (POCT). Emerging microfluidics, a …

Point-of-care-testing of nucleic acids by microfluidics

L Zhang, B Ding, Q Chen, Q Feng, L Lin… - TrAC Trends in Analytical …, 2017 - Elsevier
Nucleic acid detection offers critical information in diagnosing pathogen infection and
monitoring disease treatment. Point-of-care testing (POCT), with ideal characteristics such …

Integrated microfluidic systems with sample preparation and nucleic acid amplification

J Yin, Y Suo, Z Zou, J Sun, S Zhang, B Wang, Y Xu… - Lab on a Chip, 2019 - pubs.rsc.org
Rapid, efficient and accurate nucleic acid molecule detection is important in the screening of
diseases and pathogens, yet remains a limiting factor at point of care (POC) treatment …

Enzyme-assisted nucleic acid detection for infectious disease diagnostics: moving toward the point-of-care

A Suea-Ngam, L Bezinge, B Mateescu, PD Howes… - ACS …, 2020 - ACS Publications
Driven by complex and interconnected factors, including population growth, climate change,
and geopolitics, infectious diseases represent one of the greatest healthcare challenges of …

Point-of-care HIV viral load testing: an essential tool for a sustainable global HIV/AIDS response

PK Drain, J Dorward, A Bender, L Lillis… - Clinical microbiology …, 2019 - Am Soc Microbiol
The global public health community has set ambitious treatment targets to end the HIV/AIDS
pandemic. With the notable absence of a cure, the goal of HIV treatment is to achieve …

A rapid, instrument-free, sample-to-result nucleic acid amplification test

LK Lafleur, JD Bishop, EK Heiniger, RP Gallagher… - Lab on a Chip, 2016 - pubs.rsc.org
The prototype demonstrated here is the first fully integrated sample-to-result diagnostic
platform for performing nucleic acid amplification tests that requires no permanent …