The glycocalyx, a thick layer of carbohydrates, surrounds the cell wall of most bacterial and
parasitic pathogens. Recognition of these unique glycans by the human immune system …

Abstract The Millennium Development Goals have galvanized efforts to improve child
survival (MDG-4) and maternal health (MDG-5). There has been important progress on both …

Animals are important reservoirs of zoonotic enteropathogens, and transmission to humans
occurs more frequently in low-and middle-income countries (LMICs), where small-scale …

Background Diarrhea is known to be the major cause of mortality in children aged less than
five years old. Although mortality from diarrheal disease is decreasing globally, morbidity is …

Worldwide, pneumonia is the leading cause of death in infants and young children (aged< 5
years). We provide an overview of the global pneumonia disease burden, as well as the …

Diarrheal diseases kill 1800 children under the age of five die each day, and nearly half of
these deaths occur in sub-Saharan Africa. Contaminated drinking water and hands are two …

Diarrhea remains one of the leading causes of morbidity and mortality globally, with
enterotoxigenic Escherichia coli (ETEC) constituting a major causative pathogen. The …

Zinc (Zn) deficiency is a widespread phenomenon in agricultural soils worldwide and has a
major impact on crop yield and quality, and hence on human nutrition and health. Although …

Infections with Streptococcus pneumoniae are a major health burden. Glycoconjugate
vaccines based on capsular polysaccharides (CPSs) successfully protect from infection, but …

Background: Diarrhea remains a major cause of morbidity and mortality among children in
Tanzania. The purpose of this study was to explore associations between diarrheal disease …