Urologic chronic pelvic pain syndrome: insights from the MAPP Research Network

JQ Clemens, C Mullins, AL Ackerman… - Nature Reviews …, 2019 - nature.com
Urologic chronic pelvic pain syndrome (UCPPS), which encompasses interstitial
cystitis/bladder pain syndrome and chronic prostatitis/chronic pelvic pain syndrome, is …

Chronic prostatitis/chronic pelvic pain syndrome: a disease or symptom? Current perspectives on diagnosis, treatment, and prognosis

J Zhang, CZ Liang, X Shang… - American journal of men's …, 2020 - journals.sagepub.com
Definitive diagnosis and selection of effective treatment for chronic prostatitis/chronic pelvic
pain syndrome (CP/CPPS) are frustrations encountered frequently by urology care providers …

Urinary biomarkers in interstitial cystitis/bladder pain syndrome and its impact on therapeutic outcome

HY Lin, JH Lu, SM Chuang, KS Chueh, TJ Juan, YC Liu… - Diagnostics, 2021 - mdpi.com
Interstitial cystitis/bladder pain syndrome (IC/BPS) is defined as a chronic bladder disorder
with suprapubic pain (pelvic pain) and pressure and/or discomfort related to bladder filling …

Biomarkers in interstitial cystitis/bladder pain syndrome with and without Hunner lesion: A review and future perspectives

Y Akiyama - Diagnostics, 2021 - mdpi.com
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a debilitating urinary bladder condition
that presents with a wide variety of clinical phenotypes. It is commonly characterized by …

A bibliometric analysis of urologic chronic pelvic pain syndrome from 2000 to 2022

J Wang, B Cao, S Lin, Y Wang, Q Zhang… - Journal of Pain …, 2023 - Taylor & Francis
Purpose Urologic chronic pelvic pain syndrome has attracted a lot of attention in the new
century, and an increasing number of relevant studies have been published. Therefore, we …

Therapeutic Approaches for Urologic Chronic Pelvic Pain Syndrome; Management: Research Advances, Experimental Targets, and Future Directions

S Ashraf, T Clarkson… - Journal of Pharmacology …, 2024 - jpet.aspetjournals.org
Urologic chronic pelvic pain syndrome (UCPPS) is a painful chronic condition with persistent
pain originating from the pelvis that often leads to detrimental lifestyle changes in the …

Cannabinoid receptor 2 activation decreases severity of cyclophosphamide‐induced cystitis via regulating autophagy

Q Liu, Z Wu, Y Liu, L Chen, H Zhao… - Neurourology and …, 2020 - Wiley Online Library
Purpose Cannabinoids have been shown to exert analgesic and anti‐inflammatory effects,
and the effects of cannabinoids are mediated primarily by cannabinoid receptors 1 and 2 …

Association between urinary biomarkers MMP-7/TIMP-2 and reduced renal function in children with ureteropelvic junction obstruction

HHS Wang, PS Cho, H Zhi, SA Kostel, S DiMartino… - Plos one, 2022 - journals.plos.org
Importance Extracellular matrix proteins and enzymes involved in degradation have been
found to be associated with tissue fibrosis and ureteropelvic junction obstruction (UPJO). In …

Angiogenesis in bladder tissues is strongly correlated with urinary frequency and bladder pain in patients with interstitial cystitis/bladder pain syndrome

A Furuta, Y Suzuki, T Igarashi, Y Koike… - … Journal of Urology, 2019 - Wiley Online Library
Objectives To examine the correlation among bladder inflammation, angiogenesis, fibrosis
and urothelial denudation in biopsied bladder specimens, and O'Leary‐Sant symptom …

Cystitis-induced bladder pain is Toll-like receptor 4 dependent in a transgenic autoimmune cystitis murine model: a MAPP Research Network animal study

X Cui, X Jing, SK Lutgendorf… - American Journal …, 2019 - journals.physiology.org
Altered Toll-like receptor (TLR) 4 activation has been identified in several chronic pain
conditions but has not been well studied in interstitial cystitis/bladder pain syndrome …