Sex sorting for pest control: it's raining men!

C Lutrat, D Giesbrecht, E Marois, S Whyard… - Trends in …, 2019 - cell.com
In the pursuit of better pest-and vector-control strategies, attention returns to an old proven
technology, the sterile insect technique (SIT) and related insect population-suppression …

Of genes and genomes: mosquito evolution and diversity

L Ruzzante, MJMF Reijnders, RM Waterhouse - Trends in parasitology, 2019 - cell.com
Mosquitoes are widely despised for their exasperating buzzing and irritating bites, and more
poignantly because, during blood-feeding, females may transmit pathogens that cause …

Chromosome-level genome assemblies of the malaria vectors Anopheles coluzzii and Anopheles arabiensis

A Zamyatin, P Avdeyev, J Liang, A Sharma… - …, 2021 - academic.oup.com
Abstract Background Anopheles coluzzii and Anopheles arabiensis belong to the
Anopheles gambiae complex and are among the major malaria vectors in sub-Saharan …

Introgression of a synthetic sex ratio distortion system from Anopheles gambiae into Anopheles arabiensis

F Bernardini, A Kriezis, R Galizi, T Nolan, A Crisanti - Scientific Reports, 2019 - nature.com
I-PpoI is a homing endonuclease that has a high cleavage activity and specificity for a
conserved sequence within the ribosomal rDNA repeats, located in a single cluster on the …

Unravelling the role of mitochondrial DNA in hybrid incompatibility within species of the Anopheles gambiae complex

A Kriezis, M Vitale, G Morselli, A Crisanti… - Scientific Reports, 2024 - nature.com
Isolation mechanisms between mosquito species of the Anopheles gambiae complex, which
includes major malaria vectors, remain poorly understood. In some cases, pre-zygotic …

Y chromosome shredding in Anopheles gambiae: Insight into the cellular dynamics of a novel synthetic sex ratio distorter

M Vitale, N Kranjc, J Leigh, K Kyrou, T Courty… - PLoS …, 2024 - journals.plos.org
Despite efforts to explore the genome of the malaria vector Anopheles gambiae, the Y
chromosome of this species remains enigmatic. The large number of repetitive and …

Structural Variation of the X Chromosome Heterochromatin in the Anopheles gambiae Complex

A Sharma, NA Kinney, VA Timoshevskiy… - Genes, 2020 - mdpi.com
Heterochromatin is identified as a potential factor driving diversification of species. To
understand the magnitude of heterochromatin variation within the Anopheles gambiae …

The potential for a released autosomal X-shredder becoming a driving-Y chromosome and invasively suppressing wild populations of malaria mosquitoes

Y Alcalay, S Fuchs, R Galizi, F Bernardini… - … in Bioengineering and …, 2021 - frontiersin.org
Sex-ratio distorters based on X-chromosome shredding are more efficient than sterile male
releases for population suppression. X-shredding is a form of sex distortion that skews …

Site‐specific transgenesis of the Drosophila melanogaster Y‐chromosome using CRISPR/Cas9

A Buchman, OS Akbari - Insect molecular biology, 2019 - Wiley Online Library
Despite the importance of Y‐chromosomes in evolution and sex determination, their
heterochromatic, repeat‐rich nature makes them difficult to sequence (due, in part, to …

Hybridization between Aedes aegypti and Aedes mascarensis mosquitoes leads to disruption of male sex determination

J Liang, L Kang, P Michalak, IV Sharakhov - Communications Biology, 2024 - nature.com
Understanding the sex determination pathway and its disruptions in mosquitoes is critical for
the effective control of disease vectors through genetic manipulations based on sex …