The effect of Nigella sativa oil against the liver damage induced by Schistosoma mansoni infection in mice

MR Mahmoud, HS El-Abhar, S Saleh - Journal of ethnopharmacology, 2002 - Elsevier
It has been reported that Nigella sativa oil possesses anticestode and antinematode actions.
Besides, it produced a hepatoprotective effect in some models of liver toxicity. Therefore, our …

Genotoxic activity of praziquantel

R Montero, P Ostrosky - Mutation Research/Reviews in Mutation Research, 1997 - Elsevier
Praziquantel is a synthetic drug with a remarkable activity against parasites, particularly
treamatodes and cestodes. Initial genotoxicity tests used a spectrum of endpoints including …

Comparative in vivo antioxidant levels in Schistosoma mansoni infected mice treated with praziquantel or the essential oil of Melaleuca armillaris leaves.

M Rizk, N Ibrahim, N El-Rigal - Pakistan Journal of Biological …, 2012 - europepmc.org
Plant extracts are continuously investigated for their extensive inclusion of biologically active
constituents that exert therapeutic activities against many diseases. The aim of this study …

Propolis enhances the effectiveness of praziquantel in experimental schistosomiasis: biochemical and histopathological study

TY Mahmoud, SM Rizk, AS Maghraby… - Parasitology research, 2014 - Springer
Despite the wide current use of praziquantel (PZQ) in treatment of schistosomiasis, low cure
rates have been recorded in many studies. The aim of this study was directed to evaluate the …

Elevated levels of erythrocyte-conjugated dienes indicate increased lipid peroxidation in schistosomiasis mansoni patients

HTF Facundo, CT Brandt, JS Owen… - Brazilian Journal of …, 2004 - SciELO Brasil
Schistosoma mansoni causes liver disease by inducing granulomatous inflammation. This
favors formation of reactive oxygen species, including superoxide ions, hydrogen peroxide …

Antischistosomal activity of two active constituents isolated from the leaves of Egyptian medicinal plants

SA Ali, NS El-Regal, SM Saeed - … Diseases: Research and …, 2015 - journals.sagepub.com
Highlights D-mannitol, a naturally occurring sugar isolated from the leaves Ixora undulata
Roxb., and a linear chain pectin homogalacturonan (HG) polysaccharide isolated from the …

Schistosoma mansoni: N-acetylcysteine downregulates oxidative stress and enhances the antischistosomal activity of artemether in mice

SHS el-Din, AM Al-Hroob, FA Ebeid - Experimental Parasitology, 2011 - Elsevier
Artemether (Art), a derivative of the antimalarial artemisinin, also exhibit antischistosomal
properties. N-acetylcysteine (NAC) has a diversity of applications, largely because of the …

Dandelion (Taraxacum officinale) Improves the Therapeutic Efficiency of Praziquantel in Experimental Schistosomiasis

MTM Atwa, AM Abd-Elrazek, NIS Salem - Acta Parasitologica, 2022 - Springer
Purpose Although praziquantel (PZQ) has a wide use as an anti-schistosome agent, many of
its imperfections and side effects have been reported in many studies. The current study …

[PDF][PDF] Berberine protects against Schistosoma mansoni-induced oxidative damage in renal and testicular tissues of mice

MA Dkhil, AEA Moneim… - Pakistan Journal of …, 2014 - researchgate.net
A complex interplay between schistosomiasis and function of different organs leads to the
impairment of these organs. In this study, we demonstrated the protective effect of berberine …

[PDF][PDF] Effect of different durations of Schistosoma mansoni infection on the levels of some antioxidants in mice

M Rizk, TA Fayed, M Badawy… - Medical Journal of …, 2006 - jag.journalagent.com
The levels of lipid peroxides, glutathione, vitamin C, vitamin E catalase and superoxide
dismutase enzymes were measured in the livers of Schistosoma mansoni infected mice (CD …