Optical microscopes today have pushed the limits of speed, quality, and observable space in
biological specimens revolutionizing how we view life today. Further, specific labeling of …

Differential interference contrast (DIC) microscopy allows high-contrast, low-phototoxicity,
and label-free imaging of transparent biological objects, and has been applied in the field of …

Label‐free super‐resolution (LFSR) imaging relies on light‐scattering processes in
nanoscale objects without a need for fluorescent (FL) staining required in super‐resolved FL …

Due to its specificity, fluorescence microscopy has become a quintessential imaging tool in
cell biology. However, photobleaching, phototoxicity, and related artifacts continue to limit …

Three-dimensional (3D) refractive index (RI) tomography has recently become an exciting
new tool for biological studies. However, its limitation to (1) thin samples resulting from a …

In this paper, we review spatial light interference microscopy (SLIM), a common-path, phase-
shifting interferometer, built onto a phase-contrast microscope, with white-light illumination …

Existing approaches to evaluate cell viability involve cell staining with chemical reagents.
However, the step of exogenous staining makes these methods undesirable for rapid …

Traditional methods for cell cycle stage classification rely heavily on fluorescence
microscopy to monitor nuclear dynamics. These methods inevitably face the typical …

Fluorescence techniques dominate the field of live-cell microscopy, but bleaching and
motion blur from too long integration times limit dynamic investigations of small objects. High …

Wide-field microscopy of optically thick specimens typically features reduced contrast due to
spatial cross-talk, in which the signal at each point in the field of view is the result of a …