Prospects for in vivo Raman spectroscopy

EB Hanlon, R Manoharan, TW Koo… - Physics in Medicine …, 2000 - iopscience.iop.org
Raman spectroscopy is a potentially important clinical tool for real-time diagnosis of disease
and in situevaluation of living tissue. The purpose of this article is to review the biological …

Optical glucose sensing in biological fluids: an overview

RJ McNichols, GL Cote - Journal of biomedical optics, 2000 - spiedigitallibrary.org
Recent technological advancements in the photonics industry have led to a resurgence of
interest in optical glucose sensing and to realistic progress toward the development of an …

Flowometry in optical coherence tomography for analyte level estimation

S Reichgott, WJ Shakespeare, G Kechter… - US Patent …, 2019 - Google Patents
Optical coherence tomography (herein “OCT”) based analyte monitoring systems are
disclosed. In one aspect, techniques are disclosed that can identify fluid flow in vivo (eg …

Noninvasively measuring analyte levels in a subject

MJ Schurman, WJ Shakespeare… - US Patent 9,554,737, 2017 - Google Patents
A method for noninvasively measuring analyte levels includes using a non-imaging OCT-
based system to scan a two-dimensional area of biological tissue and gather data …

Method for data reduction and calibration of an OCT-based physiological monitor

MJ Schurman, WJ Shakespeare… - US Patent 10,130,291, 2018 - Google Patents
The present invention relates to a method and system for estimating blood analyte levels
using a noninvasive optical coherence tomography (OCT) based physiological monitor. An …

Method for data reduction and calibration of an OCT-based physiological monitor

MJ Schurman, WJ Shakespeare… - US Patent 9,078,560, 2015 - Google Patents
The present invention relates to a method and system for estimating blood analyte levels
using a noninvasive optical coherence tomography (OCT) based physiological monitor. An …

Method for data reduction and calibration of an OCT-based physiological monitor

MJ Schurman, WJ Shakespeare… - US Patent 10,791,971, 2020 - Google Patents
The present invention relates to a method and system for estimating blood analyte levels
using a noninvasive optical coherence tomography (OCT) based physiological monitor. An …

Monitoring blood constituent levels in biological tissue

MJ Schurman, WJ Shakespeare - US Patent 8,788,003, 2014 - Google Patents
In accordance with the invention, a low coherence interferometer is used to non-invasively
monitor the concentration of glucose in blood by shining a light over a surface area of …

Methods for noninvasively measuring analyte levels in a subject

MJ Schurman, WJ Shakespeare… - US Patent 8,548,549, 2013 - Google Patents
(57) ABSTRACT A method for noninvasively measuring analyte levels includes using a non-
imaging OCT-based system to Scan a two-dimensional area of biological tissue and gather …

Multispot monitoring for use in optical coherence tomography

WJ Shakespeare, WH Bennett, JT Iceman… - US Patent …, 2014 - Google Patents
Optical coherence tomography (herein “OCT”) based analyte monitoring systems are
disclosed. In one aspect, techniques are disclosed that can identify fluid flow in vivo (eg …