Environmental and genetic risk factors for MS: an integrated review

E Waubant, R Lucas, E Mowry, J Graves… - Annals of clinical …, 2019 - Wiley Online Library
Recent findings have provided a molecular basis for the combined contributions of
multifaceted risk factors for the onset of multiple sclerosis (MS). MS appears to start as a …

The role of diet in multiple sclerosis: mechanistic connections and current evidence

I Katz Sand - Current nutrition reports, 2018 - Springer
Abstract Purpose of Review This review seeks to examine current research related to the
role of diet in multiple sclerosis (MS). Recent Findings Recent research in preclinical …

Multiple sclerosis risk factors and pathogenesis

B Nourbakhsh, EM Mowry - CONTINUUM: Lifelong Learning in …, 2019 - journals.lww.com
PURPOSE OF REVIEW This article summarizes recent advances in the identification of
genetic and environmental factors that affect the risk of developing multiple sclerosis (MS) …

Evidence for a causal relationship between low vitamin D, high BMI, and pediatric-onset MS

MA Gianfrancesco, P Stridh, B Rhead, X Shao, E Xu… - Neurology, 2017 - AAN Enterprises
Objective: To utilize Mendelian randomization to estimate the causal association between
low serum vitamin D concentrations, increased body mass index (BMI), and pediatric-onset …

The role of sodium in modulating immune cell function

N Wilck, A Balogh, L Markó, H Bartolomaeus… - Nature Reviews …, 2019 - nature.com
Sodium intake is undoubtedly indispensable for normal body functions but can be
detrimental when taken in excess of dietary requirements. The consequences of excessive …

The role of dietary sodium in autoimmune diseases: The salty truth

K Sharif, H Amital, Y Shoenfeld - Autoimmunity reviews, 2018 - Elsevier
Autoimmune diseases are a group of heterogeneous condition that occur secondary to the
intrinsic loss of tolerance to self-antigens. In genetically susceptible individuals, the complex …

The modulatory effect of high salt on immune cells and related diseases

X Li, A Alu, Y Wei, X Wei, M Luo - Cell proliferation, 2022 - Wiley Online Library
Background The adverse effect of excessive salt intake has been recognized in decades.
Researchers have mainly focused on the association between salt intake and hypertension …

Contribution of dietary intake to relapse rate in early paediatric multiple sclerosis

S Azary, T Schreiner, J Graves, A Waldman… - Journal of Neurology …, 2018 - jnnp.bmj.com
Objective The role of diet in multiple sclerosis (MS) course remains largely unknown.
Children with MS have a higher relapse rate compared with MS in adults. Thus, studying the …

The role of nutritional lifestyle and physical activity in multiple sclerosis pathogenesis and management: a narrative review

S Fanara, M Aprile, S Iacono, G Schirò, A Bianchi… - Nutrients, 2021 - mdpi.com
Studies on the role of nutritional factors and physical activity (PA) in the pathogenesis of
multiple sclerosis (MS) go back a long time. Despite the intrinsic difficulty of studying their …

Sodium intake and multiple sclerosis activity and progression in BENEFIT

KC Fitzgerald, KL Munger, HP Hartung… - Annals of …, 2017 - Wiley Online Library
Objective To assess whether a high‐salt diet, as measured by urinary sodium concentration,
is associated with faster conversion from clinically isolated syndrome (CIS) to multiple …