Renal aging: causes and consequences
ED O'Sullivan, J Hughes… - Journal of the American …, 2017 - journals.lww.com
Individuals age> 65 years old are the fastest expanding population demographic throughout
the developed world. Consequently, more aged patients than before are receiving …
the developed world. Consequently, more aged patients than before are receiving …
The aging kidney: physiological changes
JR Weinstein, S Anderson - Advances in chronic kidney disease, 2010 - Elsevier
Age-associated loss of kidney function has been recognized for decades. With aging, many
subjects exhibit progressive decreases in glomerular filtration rate and renal blood flow, with …
subjects exhibit progressive decreases in glomerular filtration rate and renal blood flow, with …
Global, regional, and national burden of mortality associated with short-term temperature variability from 2000–19: a three-stage modelling study
Background Increased mortality risk is associated with short-term temperature variability.
However, to our knowledge, there has been no comprehensive assessment of the …
However, to our knowledge, there has been no comprehensive assessment of the …
Aging biology and geriatric clinical pharmacology
AJ McLean, DG Le Couteur - Pharmacological reviews, 2004 - ASPET
Population aging evokes doomsday economic and sociological prognostication, despite a
minority of older people suffering significant dependency and the potential for advances in …
minority of older people suffering significant dependency and the potential for advances in …
Age-related pharmacokinetic and pharmacodynamic changes and related risk of adverse drug reactions
A Corsonello, C Pedone… - Current medicinal …, 2010 - ingentaconnect.com
Aging is known to be associated with an increased prevalence of multiple chronic diseases,
which frequently causes the use of complex therapeutic regimens. The aging process is …
which frequently causes the use of complex therapeutic regimens. The aging process is …
The aging kidney revisited: a systematic review
D Bolignano, F Mattace-Raso, EJG Sijbrands… - Ageing research …, 2014 - Elsevier
As for the whole human body, the kidney undergoes age-related changes which translate in
an inexorable and progressive decline in renal function. Renal aging is a multifactorial …
an inexorable and progressive decline in renal function. Renal aging is a multifactorial …
[HTML][HTML] The aging kidney
XJ Zhou, D Rakheja, X Yu, R Saxena, ND Vaziri… - Kidney international, 2008 - Elsevier
Renal aging, by itself, is associated with alterations in renal morphology and a decline in
renal function, which is accelerated and/or accentuated by diseases such as diabetes …
renal function, which is accelerated and/or accentuated by diseases such as diabetes …
Acute kidney injury in older adults
S Anderson, B Eldadah, JB Halter… - Journal of the …, 2011 - journals.lww.com
Aging kidneys undergo structural and functional changes that decrease autoregulatory
capacity and increase susceptibility to acute injury. Acute kidney injury associates with …
capacity and increase susceptibility to acute injury. Acute kidney injury associates with …
Plasma uric acid level and risk for incident hypertension among men
JP Forman, H Choi, GC Curhan - Journal of the American society …, 2007 - journals.lww.com
Several studies have found that uric acid (UA) level is associated with an increased risk for
hypertension, but the association could be confounded by metabolic factors that were not …
hypertension, but the association could be confounded by metabolic factors that were not …
The aging kidney: increased susceptibility to nephrotoxicity
X Wang, JV Bonventre, AR Parrish - International journal of molecular …, 2014 - mdpi.com
Three decades have passed since a series of studies indicated that the aging kidney was
characterized by increased susceptibility to nephrotoxic injury. Data from these experimental …
characterized by increased susceptibility to nephrotoxic injury. Data from these experimental …