Satellite glial cells (SGCs) that surround sensory neurons in the peripheral nervous system
ganglia originate from neural crest cells. Although several studies have focused on SGCs …

Melanoma is the deadliest of all skin cancers due to its high metastatic potential. In recent
years, advances in targeted therapy and immunotherapy have contributed to a remarkable …

Stem cell therapies for nervous system disorders are hindered by a lack of accessible
autologous sources of neural stem cells (NSCs). In this study, neural crest–derived Schwann …

Krause corpuscles, first discovered in the 1850s, are enigmatic sensory structures with
unknown physiological properties and functions found within the genitalia and other …

The peripheral nervous system (PNS) represents a highly heterogeneous entity with a broad
range of functions, ranging from providing communication between the brain and the body to …

The neural crest shows an astonishing multipotency, generating multiple neural derivatives,
but also pigment cells, skeletogenic and other cell types. The question of how this process is …

Although rare, childhood (paediatric) cancers are a major cause of death in young children.
Unlike many adult cancers, paediatric cancers, such as neuroblastoma (NB), are …

Proper functioning of the digestive system is ensured by coordinated action of the central
and peripheral nervous systems (PNS). Peripheral innervation of the digestive system can …

Neuroblastoma is a pediatric cancer arising from the developing sympathoadrenal lineage
with complex inter-and intra-tumoral heterogeneity. To chart this complexity, we generated a …

Congenital idiopathic megaesophagus (CIM) is a gastrointestinal disorder of dogs wherein
the esophagus is dilated and swallowing activity is reduced, causing regurgitation of …