Serotonin modulates asymmetric learning from reward and punishment in healthy human volunteers

J Michely, E Eldar, A Erdman, IM Martin… - Communications …, 2022 - nature.com
Instrumental learning is driven by a history of outcome success and failure. Here, we
examined the impact of serotonin on learning from positive and negative outcomes. Healthy …

Probabilistic reward-and punishment-based learning in opioid addiction: experimental and computational data

CE Myers, J Sheynin, T Balsdon, A Luzardo… - Behavioural Brain …, 2016 - Elsevier
Addiction is the continuation of a habit in spite of negative consequences. A vast literature
gives evidence that this poor decision-making behavior in individuals addicted to drugs also …

Age affects reinforcement learning through dopamine-based learning imbalance and high decision noise—not through Parkinsonian mechanisms

RB Sojitra, I Lerner, JR Petok, MA Gluck - Neurobiology of Aging, 2018 - Elsevier
Probabilistic reinforcement learning declines in healthy cognitive aging. While some findings
suggest impairments are especially conspicuous in learning from rewards, resembling …

Altered reinforcement learning from reward and punishment in anorexia nervosa: Evidence from computational modeling

CE Wierenga, E Reilly, A Bischoff-Grethe… - Journal of the …, 2022 - cambridge.org
Objectives: Anorexia nervosa (AN) is associated with altered sensitivity to reward and
punishment. Few studies have investigated whether this results in aberrant learning. The …

Generalized anxiety disorder and social anxiety disorder, but not panic anxiety disorder, are associated with higher sensitivity to learning from negative feedback …

HY Khdour, OM Abushalbaq, IT Mughrabi… - Frontiers in integrative …, 2016 - frontiersin.org
Anxiety disorders, including generalized anxiety disorder (GAD), social anxiety disorder
(SAD), and panic anxiety disorder (PAD), are a group of common psychiatric conditions …

Effects of categorical and numerical feedback on category learning

AC Cornwall, T Davis, KA Byrne, DA Worthy - Cognition, 2022 - Elsevier
Real-world learning signals often come in the form of a continuous range of rewards or
punishments, such as receiving more or less money or other reward. However, in laboratory …

Valence and magnitude ambiguity in feedback processing

R Gu, X Feng, LS Broster, L Yuan, P Xu… - Brain and …, 2017 - Wiley Online Library
Background Outcome feedback which indicates behavioral consequences are crucial for
reinforcement learning and environmental adaptation. Nevertheless, outcome information in …

Reward and Punishment Learning as Predictors of Cognitive Behavioral Therapy Response in Parkinson's Disease Comorbid with Clinical Depression

R Perskaudas, CE Myers, A Interian… - Journal of Geriatric …, 2024 - journals.sagepub.com
Depression is highly comorbid among individuals with Parkinson's Disease (PD), who often
experience unique challenges to accessing and benefitting from empirically supported …

The impact of ADHD symptom severity on reinforcement and punishment learning among adults

SSJ Morris, JS Raiker, AT Mattfeld… - Cognitive …, 2023 - Taylor & Francis
Introduction: Aberrations in feedback learning are hypothesised to contribute to the
behavioural disruptions and impairment of attention-deficit/hyperactivity disorder (ADHD) …

Perirhinal Cortex is Involved in the Resolution of Learned Approach–Avoidance Conflict Associated with Discrete Objects

S Chu, M Margerison, S Thavabalasingam… - Cerebral …, 2021 - academic.oup.com
The rodent ventral and primate anterior hippocampus have been implicated in approach–
avoidance (AA) conflict processing. It is unclear, however, whether this structure contributes …