[HTML][HTML] Pure drug nano-assemblies: A facile carrier-free nanoplatform for efficient cancer therapy

S Fu, G Li, W Zang, X Zhou, K Shi, Y Zhai - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Nanoparticulate drug delivery systems (Nano-DDSs) have emerged as possible solution to
the obstacles of anticancer drug delivery. However, the clinical outcomes and translation are …

The chemistry of boronic acids in nanomaterials for drug delivery

A Stubelius, S Lee, A Almutairi - Accounts of chemical research, 2019 - ACS Publications
Conspectus Interest in increasing drug delivery efficiency has risen over the past decade
both as a means to improve efficacy of already clinically available drugs and due to the …

Biomarker displacement activation: a general host–guest strategy for targeted phototheranostics in vivo

J Gao, J Li, WC Geng, FY Chen, X Duan… - Journal of the …, 2018 - ACS Publications
Activatable phototheranostics is highly appealing to meet the demand of precision medicine.
However, although it displays efficacy in the construction of activatable photosensitizers …

Controlled noncovalent synthesis of secondary supramolecular polymers

S Sarkar, R Laishram, D Deb… - Journal of the American …, 2023 - ACS Publications
Dynamic supramolecular polymers, with their functional similarities to classical covalent
polymers and their adaptive and self-repairing nature reminiscent of biological assemblies …

Genome editing of mutant KRAS through supramolecular polymer-mediated delivery of Cas9 ribonucleoprotein for colorectal cancer therapy

T Wan, Y Chen, Q Pan, X Xu, Y Kang, X Gao… - Journal of Controlled …, 2020 - Elsevier
CRISPR (clustered, regularly interspaced, short palindromic repeats)/CRISPR-associated
protein 9 (Cas9) system has emerged as a powerful genome-editing tool to correct genetic …

Metal-free nanoassemblies of water-soluble photosensitizer and adenosine triphosphate for efficient and precise photodynamic cancer therapy

Z Li, S Li, Y Guo, C Yuan, X Yan, KS Schanze - ACS nano, 2021 - ACS Publications
Engineering photosensitizers into stimuli-responsive supramolecular nanodrugs allows
enhanced spatiotemporal delivery and controllable release of photosensitizers, which is …

ATP‐driven synthetic supramolecular assemblies: from ATP as a template to fuel

A Mishra, S Dhiman, SJ George - Angewandte Chemie, 2021 - Wiley Online Library
Adenosine triphosphate (ATP) is a molecular unit of energy that drives various processes in
the cellular environment. In this Minireview, we discuss the potential of physical and …

Guanidinium-based “molecular glues” for modulation of biomolecular functions

R Mogaki, PK Hashim, K Okuro, T Aida - Chemical Society Reviews, 2017 - pubs.rsc.org
Molecular adhesion based on multivalent interactions plays essential roles in various
biological processes. Hence,“molecular glues” that can adhere to biomolecules may …

Efficient intracellular delivery of native proteins facilitated by preorganized guanidiniums on pillar [5] arene skeleton

S Guo, Q Huang, J Wei, S Wang, Y Wang, L Wang… - Nano Today, 2022 - Elsevier
Due to membrane impermeability of proteins, intracellular delivery of protein is of significant
challenge. Although numerous protein carriers have been reported, it remains difficult to …

Innovative strategies for enhanced tumor photodynamic therapy

G Li, Q Wang, J Liu, M Wu, H Ji, Y Qin… - Journal of Materials …, 2021 - pubs.rsc.org
Photodynamic therapy (PDT) is an approved and promising treatment approach that utilizes
a photosensitizer (PS) to produce cytotoxic reactive oxygen species (ROS) through …