Cancer is a multifactorial pathology and it represents the second leading cause of death
worldwide. In the recent years, numerous studies highlighted the dual role of the gut …

Radiogenomics designates a scientific field that addresses possible associations between
genetic germline alterations and normal tissue toxicity after radiotherapy. The ultimate aim of …

Purpose SpaceOAR, a Food and Drug Administration–approved hydrogel intended to create
a rectal–prostate space, was evaluated in a single-blind phase III trial of image guided …

Background We have recently shown that radiotherapy may not only be a successful local
and regional treatment but, when combined with MSCs, may also be a novel systemic …

The recruitment of monocytes and their differentiation into immunosuppressive cells is
associated with the low efficacy of preclinical nonconformal radiotherapy (RT) for tumors …

The radiation-induced bystander effect (RIBE) is a destructive reaction in nonirradiated cells
and is one primary factor in determining the efficacy and success of radiation therapy in the …

Objectives: High-energy Proton Beam Therapy (PBT) commenced in England in 2018 and
NHS England commissions PBT for 1.5% of patients receiving radical radiotherapy. We …

Due to the rapid increase in the availability of patient data, there is significant interest in
precision medicine that could facilitate the development of a personalized treatment plan for …

The overall goal of radiogenomics is the identification of genomic markers that are predictive
for the development of adverse effects resulting from cancer treatment with radiation. The …

Although radiation therapy is a treatment of choice for cancer, a high percentage of patients
develop adverse effects in normal tissue following radiotherapy, mainly, due to genetic …