Introduction: The search for vaccines to prevent human leishmaniasis is an active field of
investigation aimed to prevent the devastating effects of this family of diseases on human …

Leishmaniasis is a disease that ranges in severity from skin lesions to serious disfigurement
and fatal systemic infection. Resistance to infection is associated with a T-helper-1 immune …

Canine leishmaniosis is a zoonotic disease caused by Leishmania infantum. Extensive
research is currently ongoing to develop safe and effective vaccines to protect from disease …

Background The present study aims to identify antigens in protein extracts of promastigote
and amastigote-like Leishmania (Leishmania) chagasi syn. L.(L.) infantum recognized by …

Leishmaniases are neglected diseases caused by infection with Leishmania parasites and
there are currently no prophylactic vaccines. In this study, we designed in silico a synthetic …

Background The present study aimed to evaluate a hypothetical Leishmania amastigote-
specific protein (LiHyp1), previously identified by an immunoproteomic approach performed …

Leishmania infection continues to have a major impact on public health inducing significant
morbidity and mortality mostly in the poorest populations. Drug resistance, toxicity and side …

Visceral leishmaniasis (VL) or kala-azar, a vector-borne protozoan disease, shows
endemicity in larger areas of the tropical, subtropical and the Mediterranean countries. WHO …

Visceral leishmaniasis (VL) is a tropical and subtropical disease which is endemic in more
than eighty countries around the world. Leishmania infantum is one of the main causative …

Although there has been an extensive research on vaccine development over the last
decade and some vaccines have been commercialized for canine visceral leishmaniasis …