A comparative analysis of the genomes of Drosophila melanogaster, Caenorhabditis
elegans, and Saccharomyces cerevisiae—and the proteins they are predicted to encode …

Programmed cell death is a genetically regulated process of cell suicide that is central to the
development, homeostasis and integrity of multicellular organisms. Conversely, the …

The proinflammatory cytokine interleukin-1β (IL-1β) is a secreted protein that lacks a signal
peptide and does not follow currently known pathways of secretion. Its efficient release from …

Nous sommes chacun une nébuleuse vivante, un peuple hétérogène de milliards de
cellules, dont les interactions engendrent notre corps et notre esprit. Aujourd'hui, nous …

T lymphocyte death is essential for proper function of the immune system. During the decline
of an immune response, most of the activated T cells die. Cell death is also responsible for …

Caspase 12 has been cloned from rodent cells, in which it mediated apoptosis in response
to endoplasmic reticulum stress. Based on experiments with murine cells it was suggested …

XIAP, the guardian angel | Nature Reviews Molecular Cell Biology Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …

Caspases are cysteine proteases involved in apoptosis and cytokine maturation. In
erythroblasts, keratinocytes, and lens epithelial cells undergoing differentiation, enucleation …

Several studies have suggested that activated caspase-3 has properties of a cell death
executioner protease. In this study, we examined the expression of activated caspase-3 in …

Interferon alpha (IFNα) has been used in the treatment of several types of cancer for almost
30 years, yet the mechanism (s) responsible for its anti-tumoral action remains unknown. A …