Phagocytosis, degranulation and extracellular traps release by neutrophils—the current knowledge, pharmacological modulation and future prospects

B Gierlikowska, A Stachura, W Gierlikowski… - Frontiers in …, 2021 - frontiersin.org
Neutrophils are crucial elements of innate immune system, which assure host defense via a
range of effector functions, such as phagocytosis, degranulation, and NET formation. The …

Hypericin and its anticancer effects: From mechanism of action to potential therapeutic application

N Choudhary, TE Collignon, D Tewari, A Bishayee - Phytomedicine, 2022 - Elsevier
Background Emerging studies indicate that hypericin has diverse pharmacological actions
and exhibits potential for treatment of various types of cancer. Purpose The current review …

[HTML][HTML] Hypericum perforatum: Traditional uses, clinical trials, and drug interactions

SZ Nobakht, M Akaberi… - Iranian journal of …, 2022 - ncbi.nlm.nih.gov
Hypericum perforatum (Hypericaceae), known as Saint John's wort (SJW), has been used in
different systems of traditional medicine such as Chinese traditional medicine, Greek …

Valorization of bio-colorants extracted from Hypercium scabrum L. plant for sustainable and ecological coloration of wool yarns

S Safapour, LJ Rather, R Safapour, SS Mir - Heliyon, 2023 - cell.com
Recently, natural dyes are being explored all over the world as safer and highly sustainable
bio-based alternatives to synthetic dyes. Agricultural wastes and plant by-products are the …

Chemical Composition and Immunomodulatory Activity of Hypericum perforatum Essential Oils

IA Schepetkin, G Özek, T Özek, LN Kirpotina… - Biomolecules, 2020 - mdpi.com
Hypericum L.(Hypericaceae) extracts have been used for their therapeutic effects; however,
not much is known about the immunomodulatory activity of essential oils extracted from this …

Hypericum genus as a natural source for biologically active compounds

GI Caldeira, LP Gouveia, R Serrano, OD Silva - Plants, 2022 - mdpi.com
Hypericum L. genus plants are distributed worldwide, with numerous species identified
throughout all continents, except Antarctica. These plant species are currently used in …

Hyperelatolides A–D, Antineuroinflammatory Constituents with Unusual Carbon Skeletons from Hypericum elatoides

JY Xie, ZX Wang, WY Liu, HW Liu, D Li… - Journal of Natural …, 2023 - ACS Publications
Four new δ-and γ-lactone derivatives, hyperelatolides A–D (1–4, respectively), were
discovered from the aerial portions of Hypericum elatoides R. Keller. Their structures were …

Discovery from Hypericum elatoides and synthesis of hyperelanitriles as α-aminopropionitrile-containing polycyclic polyprenylated acylphloroglucinols

JY Xie, P Li, XT Yan, JM Gao - Communications Chemistry, 2024 - nature.com
The search for lead compounds with anti-neuroinflammatory activity from structurally
'optimized'natural products is a crucial and promising strategy in the quest to discover safe …

RNA helicase DEAD‐box protein 5 alleviates nonalcoholic steatohepatitis progression via tethering TSC complex and suppressing mTORC1 signaling

Y Zhang, S Ye, W Lu, J Zhong, Y Leng, T Yang… - Hepatology, 2023 - journals.lww.com
RNA helicase DEAD‐box protein 5 alleviates nonalcoholic stea... : Hepatology RNA
helicase DEAD‐box protein 5 alleviates nonalcoholic steatohepatitis progression via …

Hypericum genus cosmeceutical application–A decade comprehensive review on its multifunctional biological properties

AR Silva, O Taofiq, ICFR Ferreira, L Barros - Industrial Crops and Products, 2021 - Elsevier
Hypericum is a genus of flowering plants and presents a nearly worldwide distribution. The
relevance of its species is mainly based on the occurrence of specialised secondary …