Exposure to a variety of toxins and/or infectious agents leads to disease, degeneration and
death, often characterised by circumstances in which cells or tissues do not merely die and …

Ferroptosis has emerged as a new type of cell death in different pathological conditions,
including neurological and kidney diseases and, especially, in different types of cancer. The …

Serum ferritin (SF) levels are commonly elevated in patients with nonalcoholic fatty liver
disease (NAFLD) because of systemic inflammation, increased iron stores, or both. The aim …

Background/Aims: Patients with chronic hepatitis C (CHC) often have increased liver iron, a
condition associated with reduced sustained response to antiviral therapy, more rapid …

Porphyria cutanea tarda (PCT) is the most common form of porphyria across the world.
Unlike other forms of porphyria, which are inborn errors of metabolism, PCT is usually an …

A 55-year-old Hispanic woman with a past medical history of obesity, type 2 diabetes,
hypertension, and hyperlipidemia is referred for evaluation of asymptomatic elevation of …

Following the model of hereditary hemochromatosis, the possible role of iron overload as a
cofactor for disease progression in acquired liver diseases has been investigated with …

Cryptogenic chronic hepatitis is a disease that is unexplained by conventional clinical,
laboratory and histological findings, and it can progress to cirrhosis, develop hepatocellular …

In chronic viral hepatitis, the role of liver biopsy as a diagnostic test has seen a decline,
paralleled by its increasing importance for prognostic purposes. Nowadays, the main …

The discovery of hyperferritinemia is often fortuitous, revealed in results from a laboratory
screening or follow-up test. The aim of the diagnostic procedure is therefore to identify its …