A multidimensional approach to frailty in older people
A Pilotto, C Custodero, S Maggi, MC Polidori… - Ageing research …, 2020 - Elsevier
Frailty is an important factor determining a higher risk of adverse health outcomes in older
adults. Although scientific community in the last two decades put a lot of effort for its …
adults. Although scientific community in the last two decades put a lot of effort for its …
[HTML][HTML] Association of polypharmacy and hyperpolypharmacy with frailty states: a systematic review and meta-analysis
Abstract Purpose To investigate:(1) the cross-sectional association between polypharmacy,
hyperpolypharmacy and presence of prefrailty or frailty;(2) the risk of incident prefrailty or …
hyperpolypharmacy and presence of prefrailty or frailty;(2) the risk of incident prefrailty or …
Comparison of medication prescribing before and after the COVID-19 pandemic among nursing home residents in Ontario, Canada
MA Campitelli, SE Bronskill, LC Maclagan… - JAMA Network …, 2021 - jamanetwork.com
Importance COVID-19 has had devastating effects on the health and well-being of older
adult residents and health care professionals in nursing homes. Uncertainty about the …
adult residents and health care professionals in nursing homes. Uncertainty about the …
Prevalence and health outcomes of polypharmacy and hyperpolypharmacy in older adults with frailty: a systematic review and meta-analysis
JJY Toh, H Zhang, YY Soh, Z Zhang, XV Wu - Ageing research reviews, 2023 - Elsevier
Polypharmacy is a prevalent issue in older adults, associated with a wide range of adverse
health outcomes, amplified in those with frailty. This review aims to synthesize current …
health outcomes, amplified in those with frailty. This review aims to synthesize current …
How frail is frail? A systematic scoping review and synthesis of high impact studies
Aims While the frailty index (FI) is a continuous variable, an FI score of 0.25 has construct
and predictive validity to categorise community-dwelling older adults as frail or non-frail. Our …
and predictive validity to categorise community-dwelling older adults as frail or non-frail. Our …
Inappropriate use of clinical practices in Canada: a systematic review
JE Squires, D Cho-Young, LD Aloisio, R Bell… - CMAJ, 2022 - Can Med Assoc
Background: Inappropriate health care leads to negative patient experiences, poor health
outcomes and inefficient use of resources. We aimed to conduct a systematic review of …
outcomes and inefficient use of resources. We aimed to conduct a systematic review of …
Frailty and potentially inappropriate prescribing in older people with polypharmacy: a bi-directional relationship?
Frail older adults commonly experience multiple co-morbid illnesses and other risk factors
for potentially inappropriate prescribing. However, determination of frailty varies depending …
for potentially inappropriate prescribing. However, determination of frailty varies depending …
Comparison of FORTA, PRISCUS and EU (7)-PIM lists on identifying potentially inappropriate medication and its impact on cognitive function in multimorbid elderly …
C Krüger, I Schäfer, H van den Bussche, H Bickel… - BMJ open, 2021 - bmjopen.bmj.com
Objectives Our study aimed to assess the frequency of potentially inappropriate medication
(PIM) use (according to three PIM lists) and to examine the association between PIM use …
(PIM) use (according to three PIM lists) and to examine the association between PIM use …
Population-wide peer comparison audit and feedback to reduce antibiotic initiation and duration in long-term care facilities with embedded randomized controlled trial
Background Antibiotic overprescribing in long-term care settings is driven by prescriber
preferences and is associated with preventable harms for residents. We aimed to determine …
preferences and is associated with preventable harms for residents. We aimed to determine …
Association of polypharmacy with survival, complications, and healthcare resource use after elective noncardiac surgery: a population-based cohort study
Background Polypharmacy is increasingly prevalent in older patients and is associated with
adverse events among medical patients. The impact of polypharmacy on outcomes after …
adverse events among medical patients. The impact of polypharmacy on outcomes after …