Mechanisms of penile erection and basis for pharmacological treatment of erectile dysfunction

KE Andersson - Pharmacological reviews, 2011 - ASPET
Erection is basically a spinal reflex that can be initiated by recruitment of penile afferents,
both autonomic and somatic, and supraspinal influences from visual, olfactory, and …

An astroglial basis of major depressive disorder? An overview

Q Wang, W Jie, JH Liu, JM Yang, TM Gao - Glia, 2017 - Wiley Online Library
Depression is a chronic, recurring, and serious mood disorder that afflicts up to 20% of the
global population. The monoamine hypothesis has dominated our understanding of the …

[HTML][HTML] Paracrine-mediated neuroprotection and neuritogenesis of axotomised retinal ganglion cells by human dental pulp stem cells: comparison with human bone …

B Mead, A Logan, M Berry, W Leadbeater… - PloS one, 2014 - journals.plos.org
We have investigated and compared the neurotrophic activity of human dental pulp stem
cells (hDPSC), human bone marrow-derived mesenchymal stem cells (hBMSC) and human …

The extended granin family: structure, function, and biomedical implications

A Bartolomucci, R Possenti, SK Mahata… - Endocrine …, 2011 - academic.oup.com
The chromogranins (chromogranin A and chromogranin B), secretogranins (secretogranin II
and secretogranin III), and additional related proteins (7B2, NESP55, proSAAS, and VGF) …

[HTML][HTML] Erythropoietin re-wires cognition-associated transcriptional networks

M Singh, Y Zhao, VD Gastaldi, SM Wojcik… - Nature …, 2023 - nature.com
Recombinant human erythropoietin (rhEPO) has potent procognitive effects, likely
hematopoiesis-independent, but underlying mechanisms and physiological role of brain …

VGF as a biomarker and therapeutic target in neurodegenerative and psychiatric diseases

JP Quinn, SE Kandigian, BA Trombetta… - Brain …, 2021 - academic.oup.com
Neurosecretory protein VGF (non-acronymic) belongs to the granin family of neuropeptides.
VGF and VGF-derived peptides have been repeatedly identified in well-powered and well …

Brain-derived neurotrophic factor-induced gene expression reveals novel actions of VGF in hippocampal synaptic plasticity

J Alder, S Thakker-Varia, DA Bangasser… - Journal of …, 2003 - Soc Neuroscience
Synaptic strengthening induced by brain-derived neurotrophic factor (BDNF) is associated
with learning and is coupled to transcriptional activation. However, identification of the …

Molecular biomarkers of depression

A Gururajan, G Clarke, TG Dinan, JF Cryan - … & Biobehavioral Reviews, 2016 - Elsevier
Depression is the leading psychiatric disorder worldwide with a significant economic and
emotional strain on society. There is a need for robust biomarkers which will help improve …

Antidepressant actions of the exercise-regulated gene VGF

JG Hunsberger, SS Newton, AH Bennett, CH Duman… - Nature medicine, 2007 - nature.com
Exercise has many health benefits, including antidepressant actions in depressed human
subjects, but the mechanisms underlying these effects have not been elucidated. We used a …

Fluoxetine regulates the expression of neurotrophic/growth factors and glucose metabolism in astrocytes

I Allaman, H Fiumelli, PJ Magistretti, JL Martin - Psychopharmacology, 2011 - Springer
Rationale The pharmacological actions of most antidepressants are ascribed to the
modulation of serotonergic and/or noradrenergic transmission in the brain. During …