Chemotherapy-induced peripheral neuropathy: epidemiology, pathomechanisms and treatment

J Burgess, M Ferdousi, D Gosal, C Boon… - Oncology and …, 2021 - Springer
Purpose This review provides an update on the current clinical, epidemiological and
pathophysiological evidence alongside the diagnostic, prevention and treatment approach …

Prevention of chemotherapy-induced peripheral neuropathy: a review of recent findings

EY Ibrahim, BE Ehrlich - Critical reviews in oncology/hematology, 2020 - Elsevier
Chemotherapy-induced peripheral neuropathy (CIPN) is an adverse effect of chemotherapy
that is frequently experienced by patients receiving treatment for cancer. CIPN is caused by …

Sarm1 activation produces cADPR to increase intra-axonal Ca++ and promote axon degeneration in PIPN

Y Li, MF Pazyra-Murphy, D Avizonis… - Journal of Cell …, 2021 - rupress.org
Cancer patients frequently develop chemotherapy-induced peripheral neuropathy (CIPN), a
painful and long-lasting disorder with profound somatosensory deficits. There are no …

Platinum‐induced peripheral neurotoxicity: from pathogenesis to treatment

NP Staff, G Cavaletti, B Islam… - Journal of the …, 2019 - Wiley Online Library
Platinum‐induced peripheral neurotoxicity (PIPN) is a common side effect of platinum‐
based chemotherapy that may cause dose reduction and discontinuation, with oxaliplatin …

Chemotherapy-induced peripheral neuropathy: part 1—current state of knowledge and perspectives for pharmacotherapy

K Sałat - Pharmacological reports, 2020 - Springer
Background Despite the increasing knowledge of the etiology of neuropathic pain, this type
of chronic pain is resistant to available analgesics in approximately 50% of patients and …

Chemotherapy-induced peripheral neuropathy—part 2: focus on the prevention of oxaliplatin-induced neurotoxicity

K Sałat - Pharmacological Reports, 2020 - Springer
Background Chemotherapy-induced peripheral neuropathy (CIPN) is regarded as one of the
most common dose-limiting adverse effects of several chemotherapeutic agents, such as …

Targeting strategies for oxaliplatin-induced peripheral neuropathy: clinical syndrome, molecular basis, and drug development

Y Yang, B Zhao, X Gao, J Sun, J Ye, J Li… - Journal of experimental & …, 2021 - Springer
Oxaliplatin (OHP)-induced peripheral neurotoxicity (OIPN) is a severe clinical problem and
potentially permanent side effect of cancer treatment. For the management of OIPN, accurate …

Risk factors for chemotherapy‐induced peripheral neuropathy in patients receiving taxane‐and platinum‐based chemotherapy

A Molassiotis, HL Cheng, KT Leung, YC Li… - Brain and …, 2019 - Wiley Online Library
Background Chemotherapy‐induced peripheral neuropathy (CIPN) is a significant and
difficult to manage side effect of neurotoxic chemotherapies. Several risk factors for CIPN …

Overview and critical revision of clinical assessment tools in chemotherapy‐induced peripheral neurotoxicity

SB Park, P Alberti, NA Kolb… - Journal of the …, 2019 - Wiley Online Library
Chemotherapy‐induced peripheral neurotoxicity (CIPN) is a major toxicity of cancer
treatment, leading to dose reduction and premature treatment cessation, potentially affecting …

Updates in the treatment of chemotherapy-induced peripheral neuropathy

JN Mezzanotte, M Grimm, NV Shinde, T Nolan… - … treatment options in …, 2022 - Springer
Opinion statement Chemotherapy-induced peripheral neuropathy (CIPN) is a common
toxicity associated with treatment with platinum-based agents, taxanes, vinca alkaloids, and …