▪ Abstract Embryological and genetic studies of mouse, bird, zebrafish, and frog embryos are
providing new insights into the regulatory functions of the myogenic regulatory factors …

Research in the past year has added to our understanding of the signalling systems that
specify myogenic identity in the embryo and of the regulation and roles of MyoD family …

Unraveling the complex tissue interactions necessary to generate the structural and
functional diversity present among craniofacial muscles is challenging. These muscles …

Skeletal muscle has an intrinsic capacity for regeneration following injury or exercise. The
presence of adult stem cells in various tissues with myogenic potential provides new …

Although skeletal muscles appear superficially alike at different anatomical locations, in
reality there is considerably more diversity than previously anticipated. Heterogeneity is not …

Increasing evidence in the last years indicates that the vast amount of regulatory information
contained in mammalian genomes is organized in precise 3D chromatin structures …

We address the molecular control of myogenesis in progenitor cells derived from the
hypaxial somite. Null mutations in Pax3, a key regulator of skeletal muscle formation, lead to …

Reciprocal defects in signaling between the myotome and the sclerotome compartments of
the somites in PDGFR αand Myf5 mutant embryos lead to alterations in the formation of the …

Formation and remodeling of the pharyngeal arches play central roles in craniofacial
development. TBX1, encoding a T-box-containing transcription factor, is the major candidate …

Pax3 and Pax7 regulate stem cell function in skeletal myogenesis. However, molecular
insight into their distinct roles has remained elusive. Using gene expression data combined …