Review of meningococcal group B vaccines
DM Granoff - Clinical infectious diseases, 2010 - academic.oup.com
No broadly effective vaccines are available for prevention of group B meningococcal
disease, which accounts for> 50% of all cases. The group B capsule is an autoantigen and …
disease, which accounts for> 50% of all cases. The group B capsule is an autoantigen and …
Role of factor H binding protein in Neisseria meningitidis virulence and its potential as a vaccine candidate to broadly protect against meningococcal disease
LK McNeil, RJ Zagursky, SL Lin, E Murphy… - Microbiology and …, 2013 - Am Soc Microbiol
Neisseria meningitidis is a Gram-negative microorganism that exists exclusively in humans
and can cause devastating invasive disease. Although capsular polysaccharide-based …
and can cause devastating invasive disease. Although capsular polysaccharide-based …
The meningococcal vaccine candidate neisserial surface protein A (NspA) binds to factor H and enhances meningococcal resistance to complement
LA Lewis, J Ngampasutadol, R Wallace… - PLoS …, 2010 - journals.plos.org
Complement forms an important arm of innate immunity against invasive meningococcal
infections. Binding of the alternative complement pathway inhibitor factor H (fH) to fH-binding …
infections. Binding of the alternative complement pathway inhibitor factor H (fH) to fH-binding …
Bexsero: a multicomponent vaccine for prevention of meningococcal disease
AR Gorringe, R Pajón - Human vaccines & immunotherapeutics, 2012 - Taylor & Francis
Serogroup B meningococcal (MenB) disease remains a serious public health problem for
which a cross-protective vaccine effective against a wide range of MenB isolates has not …
which a cross-protective vaccine effective against a wide range of MenB isolates has not …
The Discovery and Development of a Novel Vaccine to Protect against Neisseria meningitidis Serogroup B Disease
GW Zlotnick, TR Jones, P Liberator, L Hao… - Human vaccines & …, 2015 - Taylor & Francis
Vaccines have had a major impact on the reduction of many diseases globally. Vaccines
targeted against invasive meningococcal disease (IMD) due to serogroups A, C, W, and Y …
targeted against invasive meningococcal disease (IMD) due to serogroups A, C, W, and Y …
Meningococcal vaccines
DM Granoff, S Pelton, LH Harrison - Vaccines. 6th ed …, 2012 - books.google.com
The dominant clinical features of meningococcal disease are fever, rash, and meningitis, but
the initial signs and symptoms are often nonspecific and therefore may be indistinguishable …
the initial signs and symptoms are often nonspecific and therefore may be indistinguishable …
Pathogenesis of meningococcemia
M Coureuil, O Join-Lambert… - Cold Spring …, 2013 - perspectivesinmedicine.cshlp.org
Neisseria meningitidis is responsible for two major diseases: cerebrospinal meningitis
and/or septicemia. The latter can lead to a purpura fulminans, an often-fatal condition owing …
and/or septicemia. The latter can lead to a purpura fulminans, an often-fatal condition owing …
Neisseria meningitidis factor H-binding protein fHbp: a key virulence factor and vaccine antigen
KL Seib, M Scarselli, M Comanducci… - Expert review of …, 2015 - Taylor & Francis
Neisseria meningitidis is a leading cause of meningitis and sepsis worldwide. The first broad-
spectrum multicomponent vaccine against serogroup B meningococcus (MenB), 4CMenB …
spectrum multicomponent vaccine against serogroup B meningococcus (MenB), 4CMenB …
Human and veterinary vaccines for Lyme disease
NS O'Bier, AL Hatke, AC Camire… - Current issues in molecular …, 2021 - mdpi.com
Lyme disease (LD) is an emerging zoonotic infection that is increasing in incidence in North
America, Europe, and Asia. With the development of safe and efficacious vaccines, LD can …
America, Europe, and Asia. With the development of safe and efficacious vaccines, LD can …
[HTML][HTML] A broadly-protective vaccine against meningococcal disease in sub-Saharan Africa based on generalized modules for membrane antigens (GMMA)
O Koeberling, E Ispasanie, J Hauser, O Rossi… - Vaccine, 2014 - Elsevier
Introduction Neisseria meningitidis causes epidemics of meningitis in sub-Saharan Africa.
These have mainly been caused by capsular group A strains, but W and X strains are …
These have mainly been caused by capsular group A strains, but W and X strains are …