Mechanisms of phagocytosis in macrophages
A Aderem, DM Underhill - Annual review of immunology, 1999 - annualreviews.org
▪ Abstract Phagocytosis of pathogens by macrophages initiates the innate immune
response, which in turn orchestrates the adaptive response. In order to discriminate between …
response, which in turn orchestrates the adaptive response. In order to discriminate between …
The myristoyl-electrostatic switch: a modulator of reversible protein-membrane interactions
S McLaughlin, A Aderem - Trends in biochemical sciences, 1995 - cell.com
Hydrophobic insertion of the acyl chain into the bilayer is necessary but not sufficient for the
membrane binding of a myristoylated protein. The myristoylated alanine-rich C kinase …
membrane binding of a myristoylated protein. The myristoylated alanine-rich C kinase …
Molecular definition of distinct cytoskeletal structures involved in complement-and Fc receptor-mediated phagocytosis in macrophages.
It has long been known from the results of ultrastructural studies that complement-and
immunoglobulin G (IgG)-opsonized particles are phagocytosed differently by macrophages …
immunoglobulin G (IgG)-opsonized particles are phagocytosed differently by macrophages …
Inhibition of Phagolysosomal Biogenesis by the Leishmania Lipophosphoglycan
M Desjardins, A Descoteaux - The Journal of experimental medicine, 1997 - rupress.org
Whereas amastigotes of the protozoan parasite Leishmania proliferate inside acidic
phagolysosomal vacuoles of the macrophage, vacuoles induced by Leishmania donovani …
phagolysosomal vacuoles of the macrophage, vacuoles induced by Leishmania donovani …
Cross-talk unfolded: MARCKS proteins
A Arbuzova, AAP Schmitz, G Vergères - Biochemical Journal, 2002 - portlandpress.com
The proteins of the MARCKS (myristoylated alanine-rich C kinase substrate) family were first
identified as prominent substrates of protein kinase C (PKC). Since then, these proteins …
identified as prominent substrates of protein kinase C (PKC). Since then, these proteins …
The role of neutrophils and monocytes in innate immunity
C Kantari, M Pederzoli-Ribeil… - Trends in innate immunity, 2008 - karger.com
Polymorphonuclear neutrophils (PMNs) and monocyte/macrophages (MMs) are
professional phagocytic cells that are able to phagocytose and destroy infectious agents …
professional phagocytic cells that are able to phagocytose and destroy infectious agents …
Virulent Strains of Helicobacter pylori Demonstrate Delayed Phagocytosis and Stimulate Homotypic Phagosome Fusion in Macrophages
LAH Allen, LS Schlesinger, B Kang - The Journal of experimental …, 2000 - rupress.org
Helicobacter pylori colonizes the gastric epithelium of∼ 50% of the world's population and
plays a causative role in the development of gastric and duodenal ulcers. H. pylori is …
plays a causative role in the development of gastric and duodenal ulcers. H. pylori is …
A role for MARCKS, the alpha isozyme of protein kinase C and myosin I in zymosan phagocytosis by macrophages.
LH Allen, A Aderem - The Journal of experimental medicine, 1995 - rupress.org
Myristoylated, alanine-rich C-kinase substrate (MARCKS) is a lipopolysaccharide-induced
protein kinase C (PKC) substrate that has been proposed to regulate actin-membrane …
protein kinase C (PKC) substrate that has been proposed to regulate actin-membrane …
Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling
Failure of oligodendrocyte precursor cell (OPC) differentiation contributes significantly to
failed myelin sheath regeneration (remyelination) in chronic demyelinating diseases …
failed myelin sheath regeneration (remyelination) in chronic demyelinating diseases …