Control and analysis of protein aggregation is an increasing challenge to pharmaceutical
research and development. Due to the nature of protein interactions, protein aggregation …

Analytical ultracentrifugation (AUC) is a versatile and powerful method for the quantitative
analysis of macromolecules in solution. AUC has broad applications for the study of …

The analysis of analytical ultracentrifugation (AUC) data has been greatly facilitated by the
advances accumulated in recent years. These improvements include refinements in AUC …

SAMHD1, an analogue of the murine interferon (IFN)-γ-induced gene Mg11 (ref.), has
recently been identified as a human immunodeficiency virus-1 (HIV-1) restriction factor that …

DNMDP and related compounds, or velcrins, induce complex formation between the
phosphodiesterase PDE3A and the SLFN12 protein, leading to a cytotoxic response in …

Invasion of host erythrocytes is essential to the life cycle of Plasmodium parasites and
development of the pathology of malaria. The stages of erythrocyte invasion, including initial …

The mechanism by which newly synthesized histones are imported into the nucleus and
deposited onto replicating chromatin alongside segregating nucleosomal counterparts is …

Multisite interactions and the formation of ternary or higher‐order protein complexes are
ubiquitous features of protein interactions. Cooperativity between different ligands is a …

Modern computational strategies have allowed for the direct modeling of the sedimentation
process of heterogeneous mixtures, resulting in sedimentation velocity (SV) size‐distribution …

The causative agent of Legionnaires disease, Legionella pneumophila, forms a replicative
vacuole in phagocytes by means of the intracellular multiplication/defective organelle …