Neuraminidase inhibitors for preventing and treating influenza in adults and children

T Jefferson, MA Jones, P Doshi… - Cochrane database …, 2014 - cochranelibrary.com
Background Neuraminidase inhibitors (NIs) are stockpiled and recommended by public
health agencies for treating and preventing seasonal and pandemic influenza. They are …

Neuraminidase inhibitors for preventing and treating influenza in healthy adults: systematic review and meta-analysis

T Jefferson, M Jones, P Doshi, C Del Mar - Bmj, 2009 - bmj.com
Objectives To update a 2005 Cochrane review that assessed the effects of neuraminidase
inhibitors in preventing or ameliorating the symptoms of influenza, the transmission of …

Comparison of antiviral agents for seasonal influenza outcomes in healthy adults and children: a systematic review and network meta-analysis

JW Liu, SH Lin, LC Wang, HY Chiu, JA Lee - JAMA network open, 2021 - jamanetwork.com
Importance Antiviral treatment of influenza is recommended for patients with influenza-like
illness during periods of community cocirculation of influenza viruses and SARS-CoV-2; …

Design and performance testing of quantitative real time PCR assays for influenza A and B viral load measurement

CL Ward, MH Dempsey, CJA Ring, RE Kempson… - Journal of clinical …, 2004 - Elsevier
Background: The antiviral effect of anti-influenza drugs such as zanamivir may be
demonstrated in patients as an increased rate of decline in viral load over a time course of …

Antivirals for influenza in healthy adults: systematic review

T Jefferson, V Demicheli, D Rivetti, M Jones… - The Lancet, 2006 - thelancet.com
Background Use of antivirals is recommended for the control of seasonal and pandemic
influenza. Our aim was to review the evidence of efficacy, effectiveness, and safety of …

Restoring invisible and abandoned trials: a call for people to publish the findings

P Doshi, K Dickersin, D Healy, SS Vedula, T Jefferson - Bmj, 2013 - bmj.com
Unpublished and misreported studies make it difficult to determine the true value of a
treatment. Peter Doshi and colleagues call for sponsors and investigators of abandoned …

Neuraminidase inhibitors for preventing and treating influenza in healthy adults

T Jefferson, MA Jones, P Doshi… - Cochrane Database …, 2006 - cochranelibrary.com
Background Neuraminidase inhibitors (NI) are recommended for use against influenza and
its complications in inter‐pandemic years and during pandemics. Objectives To assess the …

A phase II study of DAS181, a novel host directed antiviral for the treatment of influenza infection

RB Moss, C Hansen, RL Sanders… - The Journal of …, 2012 - academic.oup.com
Background. DAS181, a novel host-directed antiviral in development for influenza treatment,
was assessed in this phase II clinical trial. Methods. This study was a double-blind, placebo …

The value of neuraminidase inhibitors for the prevention and treatment of seasonal influenza: a systematic review of systematic reviews

B Michiels, K Van Puyenbroeck, V Verhoeven… - PloS one, 2013 - journals.plos.org
Controversy has arisen regarding the effectiveness of neuraminidase inhibitors (NIs),
especially against influenza-related complications. A literature search was performed to …

WHO Rapid Advice Guidelines for pharmacological management of sporadic human infection with avian influenza A (H5N1) virus

HJ Schünemann, SR Hill, M Kakad… - The Lancet infectious …, 2007 - thelancet.com
Recent spread of avian influenza A (H5N1) virus to poultry and wild birds has increased the
threat of human infections with H5N1 virus worldwide. Despite international agreement to …