Dietary polyphenols have been the focus of major interest for their potential benefits on
human health. Several preclinical studies have been conducted to provide a rationale for …

S100B is a Ca2+‐binding protein mainly concentrated in astrocytes. Its levels in biological
fluids (cerebrospinal fluid, peripheral and cord blood, urine, saliva, amniotic fluid) are …

Astrocytes are key cellular partners for neurons in the central nervous system. Astrocytes
react to virtually all types of pathological alterations in brain homeostasis by significant …

MicroRNAs (miRNAs) are non-coding RNAs which are essential post-transcriptional gene
regulators in various neuronal degenerative diseases and playact a key role in these …

With the industrial development and progressive increase in environmental pollution, the
mankind overexposure to heavy metals emerges as a pressing public health issue …

Early life stress (ELS) induces long-term phenotypic adaptations that contribute to increased
vulnerability to a host of neuropsychiatric disorders. Epigenetic mechanisms, including DNA …

Abstract Alzheimer's disease (AD), the most frequent cause of dementia, is escalating as a
global epidemic, and so far, there is neither cure nor treatment to alter its progression. The …

Glial cells outnumber neurons in the brain and play important roles in the neuroinflammation
that accompanies brain damage in neurodegenerative diseases. In Parkinson's disease …

Astrocytes are specialized non-neuronal glial cells of the central nervous system,
contributing to neuronal excitability and synaptic transmission (gliotransmission). Astrocytes …

Neuroinflammation is one of the main contributors to the onset and progression of
neurodegenerative diseases such as Alzheimer's and Parkinson's diseases. Microglial and …