Despite recent progress in understanding the cancer genome, there is still a relative delay in
understanding the full aspects of the glycome and glycoproteome of cancer. Glycobiology …

Decades of research have disclosed a plethora of alterations in protein glycosylation that
decisively impact in all stages of disease and ultimately contribute to more aggressive cell …

Aberrant glycosylation plays a fundamental role in key pathological steps of tumour
development and progression. Glycans have roles in cancer cell signalling, tumour cell …

Tumour metastasis is the main cause of cancer related deaths. Metastasis is an intricate
multi-step process that requires the acquisition of several cancer cell features, including the …

E-cadherin and P-cadherin are major contributors to cell–cell adhesion in epithelial tissues,
playing pivotal roles in important morphogenetic and differentiation processes during …

Simple Summary The detection of colorectal cancer (CRC) at an early stage is increasing
due to the implementation of screening programs. Local excision of early CRC is potentially …

E‐cadherin protein (CDH1 gene) integrity is fundamental to the process of epithelial
polarization and differentiation. Deregulation of the E‐cadherin function plays a crucial role …

Glycosylation is among the most important post-translational modifications for proteins and
is of intrinsic complex character compared with DNAs and naked proteins. Indeed, over 50 …

Background One of the new roles for enzymes in personalized medicine builds on a rational
approach to cancer biomarker discovery using enzyme-associated aberrant glycosylation. A …

Purpose The prognosis of gastric cancer (GC) is poor, and the molecular pathogenesis
players are vastly unknown. Surgery remains the primary option in GC treatment. The aim of …