Inflammation is a natural defence response of the immune system against environmental
insult, stress and injury, but hyper-and hypo-inflammatory responses can trigger diseases …

The suicide death toll is alarmingly high, outnumbering deaths from war and homicide
worldwide (1). Many factors contribute to suicide death, making it difficult to prevent because …

Coronavirus disease 2019 (COVID-19) is caused by the Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2). The impacts of the disease may be beyond the …

Inflammatory illness is associated with depression. Preclinical work has shown that
chemokines are linked with peripheral–central crosstalk and may be important in mediating …

Consistent evidence indicates the association between inflammatory markers and suicidal
behavior. The burden related to immunological differences have been widely documented in …

A meta-analysis showed a significant association between activated immune-inflammatory
and nitro-oxidative (IO&NS) pathways and suicide attempts (SA). There is no data on …

Brain gene expression profiling studies of suicide and depression using oligonucleotide
microarrays have often failed to distinguish these two phenotypes. Moreover, next …

Objective Immune dysregulation has been implicated in depression and other psychiatric
disorders. What is less clear is how immune dysregulation can affect risk of suicidal …

Background Suicide attempts (SA) frequently occur in patients with mood disorders and
schizophrenia, which are both accompanied by activated immune-inflammatory and nitro …

BackgroundSleep disturbance has been consistently identified as an independent
contributor to suicide risk. Inflammation has emerged as a potential mechanism linked to …