The two-stage molecular scenery of SARS-CoV-2 infection with implications to disease severity: An in-silico quest

G Potamias, P Gkoublia, A Kanterakis - Frontiers in Immunology, 2023 - frontiersin.org
Introduction The two-stage molecular profile of the progression of SARS-CoV-2 (SCOV2)
infection is explored in terms of five key biological/clinical questions:(a) does SCOV2 …

Machine learning versus multivariate logistic regression for predicting severe COVID‐19 in hospitalized children with Omicron variant infection

P Liu, Z Xing, X Peng, M Zhang, C Shu… - Journal of Medical …, 2024 - Wiley Online Library
With the emergence of the Omicron variant, the number of pediatric Coronavirus Disease
2019 (COVID‐19) cases requiring hospitalization and developing severe or critical illness …

Obesity fosters severe disease outcomes in a mouse model of coronavirus infection associated with transcriptomic abnormalities

P Rai, JM Marano, L Kang… - Journal of Medical …, 2024 - Wiley Online Library
Obesity has been identified as an independent risk factor for severe outcomes in humans
with coronavirus disease 2019 (COVID‐19) and other infectious diseases. Here, we …

Revealing disease subtypes and heterogeneity in common variable immunodeficiency through transcriptomic analysis

MR Zabihi, Z Moradi, N Safari, Z Salehi, K Kavousi - Scientific Reports, 2024 - nature.com
Abstract Common Variable Immunodeficiency (CVID) is a primary immunodeficiency
characterized by reduced levels of specific immunoglobulins, resulting in frequent infections …

Progress of the “Molecular Informatics” Section in 2022

A Rescifina - International Journal of Molecular Sciences, 2023 - mdpi.com
This is the first Editorial of the “Molecular Informatics” Section (MIS) of the International
Journal of Molecular Sciences (IJMS), which was created towards the end of 2018 (the first …

AI: Catalyst for Drug Discovery and Development

K Nailwal, S Durgapal, K Dasauni… - … Biotechnology and Drug …, 2024 - Springer
This abstract explores the multifaceted roles of AI in expediting the drug development
process. AI-driven algorithms analyze vast datasets, unraveling complex biological …

Deepcovid-fuse: A multi-modality deep learning model fusing chest x-rays and clinical variables to predict covid-19 risk levels

Y Wu, A Dravid, RM Wehbe, AK Katsaggelos - Bioengineering, 2023 - mdpi.com
The COVID-19 pandemic has posed unprecedented challenges to global healthcare
systems, highlighting the need for accurate and timely risk prediction models that can …