Pain associated with mechanical, chemical, and thermal heat stimulation of the ocular
surface is mediated by trigeminal ganglion neurons, while cold thermoreceptors detect …

The cornea is the most sensitive structure in the human body. Corneal nerves adapt to
maintain transparency and contribute to corneal health by mediating tear secretion and …

Corneal nerves are responsible for the sensations of touch, pain, and temperature and play
an important role in the blink reflex, wound healing, and tear production and secretion …

This review provides a comprehensive analysis of the structure, neurochemical content, and
functions of corneal nerves, with special emphasis on human corneal nerves. A revised …

The choroid is richly innervated by parasympathetic, sympathetic and trigeminal sensory
nerve fibers that regulate choroidal blood flow in birds and mammals, and presumably other …

A renewed interest in the characteristics and neural basis of corneal and conjunctival
sensations is developing in recent years due to the high incidence of discomfort and altered …

purpose. Corneal wound healing is impaired in diabetic cornea. The purpose of this study
was to examine patients with type 1 diabetes mellitus for changes in corneal morphology …

purpose. Tear film instability and tear hyperosmolarity are considered core mechanisms in
the development of dry eye. The authors hypothesize that evaporation and instability …

The purpose of this study was to examine ocular symptoms that have been associated with
dry eye among contact lens wearers. A dry eye questionnaire was administered at random …

Mammalian Piezo2 channels are essential for transduction of innocuous mechanical forces
by proprioceptors and cutaneous touch receptors. In contrast, mechanical responses of …