Understanding communication and information processing in nervous systems is a central
goal of neuroscience. Over the past two decades, advances in connectomics and network …

The principle of targeting brain circuits has drawn increasing attention with the growth of
brain stimulation treatments such as transcranial magnetic stimulation (TMS), deep brain …

Transcranial magnetic stimulation (TMS) is used to treat multiple psychiatric and
neurological conditions by manipulating activity in particular brain networks and circuits, but …

Neuromodulation trials for the treatment of posttraumatic stress disorder (PTSD) have
yielded mixed results, and the optimal neuroanatomical target remains unclear. Here we …

Few articles appearing in medical journals provide more important information than
randomized controlled trials (RCTs). Readers are in for a rare treat by encountering two …

The healthy functioning of the human brain depends on the balanced interaction of its
neuronal subsystems. In many serious disorders in which this balance is compromised …

The vision of biologically tailored treatment for mental illness has inspired clinical
neuroscience since the days of Kraepelin and Alzheimer. In recent decades, large-scale …

Nervous systems are evidently complex networks on multiple spatial scales, from the
microscopic scale of synaptically connected neuronal networks to the macroscopic scale of …

TO THE EDITOR: I read with interest the recent article by Brown and colleagues,“Time for
Brain Medicine”(1). The authors begin with a compelling argument that having two clinical …

Background Deep brain stimulation (DBS) has shown individual promise in treating
treatment resistant depression (TRD), but larger-scale trials have been less successful …