Comparative genomics has recently provided unprecedented insights into the biology and
evolution of the fungal lineage. In the postgenomics era, a major research interest focuses …

The eukaryotic genome must be precisely organized for its proper function, as genome
topology impacts transcriptional regulation, cell division, replication, and repair, among other …

UPF-1-UPF-2-UPF-3 complex-orchestrated nonsense-mediated mRNA decay (NMD) is a
well-characterized eukaryotic cellular surveillance mechanism that not only degrades …

Heterochromatin is a key feature of eukaryotic genomes and is crucial for maintaining
genomic stability. In fission yeast, heterochromatin nucleation is mainly mediated by DNA …

Crucial mechanisms are required to restrict self-propagating heterochromatin spreading
within defined boundaries and prevent euchromatic gene silencing. In the filamentous …

In eukaryotes, deposition of the histone variant H2A. Z into nucleosomes through the
chromatin remodeling complex, SWR1, is a crucial step in modulating gene transcription …

Background Organization of the eukaryotic genome is essential for proper function,
including gene expression. In metazoans, chromatin loops and Topologically Associated …

Abstract Negative cofactor 2 (NC2), including two subunits NC2α and NC2β, is a conserved
positive/negative regulator of class II gene transcription in eukaryotes. It is known that NC2 …

A key factor influencing consumer acceptance of soybean products is the aroma and taste
profile, which can be modulated through fermentation using unique microbial strains. This …

The spindle assembly checkpoint factors Bub3 and BuGZ play critical roles in mitotic
process, but little is known about their roles in other cellular processes in eukaryotes. In …