Cardiovascular complications in chronic kidney disease: a review from the European Renal and Cardiovascular Medicine Working Group of the European Renal …

C Zoccali, F Mallamaci, M Adamczak… - Cardiovascular …, 2023 - academic.oup.com
Chronic kidney disease (CKD) is classified into five stages with kidney failure being the most
severe stage (stage G5). CKD conveys a high risk for coronary artery disease, heart failure …

Vascular calcification in CKD-MBD: Roles for phosphate, FGF23, and Klotho

S Yamada, CM Giachelli - Bone, 2017 - Elsevier
Vascular calcification (VC) is highly prevalent in aging, diabetes mellitus, and chronic kidney
disease (CKD). VC is a strong predictor of cardiovascular morbidity and mortality in the CKD …

Coronary artery calcification and risk of cardiovascular disease and death among patients with chronic kidney disease

J Chen, MJ Budoff, MP Reilly, W Yang… - JAMA …, 2017 - jamanetwork.com
Importance Coronary artery calcification (CAC) is highly prevalent in dialysis-naive patients
with chronic kidney disease (CKD). However, there are sparse data on the association of …

[HTML][HTML] LRP5 and LRP6 in Wnt signaling: similarity and divergence

Q Ren, J Chen, Y Liu - Frontiers in cell and developmental biology, 2021 - frontiersin.org
The canonical Wnt/β-catenin signaling plays a fundamental role in regulating embryonic
development, injury repair and the pathogenesis of human diseases. In vertebrates, low …

A current understanding of vascular calcification in CKD

NJ Paloian, CM Giachelli - American Journal of Physiology …, 2014 - journals.physiology.org
Patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD) have
significant cardiovascular morbidity and mortality that is in part due to the development of …

[HTML][HTML] Epidemiology of cardiovascular risk in chronic kidney disease patients: the real silent killer

M Provenzano, G Coppolino, T Faga… - Reviews in …, 2019 - imrpress.com
Chronic kidney disease is a growing public health problem, as its prevalence and incidence
have almost doubled over the last three decades. Chronic kidney disease is defined as the …

[HTML][HTML] Cardiotoxicity of uremic toxins: a driver of cardiorenal syndrome

S Lekawanvijit - Toxins, 2018 - mdpi.com
Cardiovascular disease (CVD) is highly prevalent in the setting of chronic kidney disease
(CKD). Such coexistence of CVD and CKD—the so-called “cardiorenal or renocardiac …

[HTML][HTML] Phytate intake, health and disease:“let thy food be thy medicine and medicine be thy food”

A Pujol, P Sanchis, F Grases, L Masmiquel - Antioxidants, 2023 - mdpi.com
Phytate (myo-inositol hexakisphosphate or InsP6) is the main phosphorus reservoir that is
present in almost all wholegrains, legumes, and oilseeds. It is a major component of the …

[HTML][HTML] FGF23 and phosphate–cardiovascular toxins in CKD

I Vogt, D Haffner, M Leifheit-Nestler - Toxins, 2019 - mdpi.com
Elevated levels of fibroblast growth factor 23 (FGF23) and phosphate are highly associated
with increased cardiovascular disease and mortality in patients suffering from chronic kidney …

Prevalence of coronary artery calcification and its association with mortality, cardiovascular events in patients with chronic kidney disease: a systematic review and …

XR Wang, JJ Zhang, XX Xu, YG Wu - Renal Failure, 2019 - Taylor & Francis
Purpose: To date, the prevalence and prognostic role of coronary artery calcification (CAC)
in patients with chronic kidney disease (CKD) have been investigated in several studies, but …