Peptide-based supramolecular systems chemistry

F Sheehan, D Sementa, A Jain, M Kumar… - Chemical …, 2021 - ACS Publications
Peptide-based supramolecular systems chemistry seeks to mimic the ability of life forms to
use conserved sets of building blocks and chemical reactions to achieve a bewildering array …

Enzymatic noncovalent synthesis

H He, W Tan, J Guo, M Yi, AN Shy, B Xu - Chemical reviews, 2020 - ACS Publications
Enzymatic reactions and noncovalent (ie, supramolecular) interactions are two fundamental
nongenetic attributes of life. Enzymatic noncovalent synthesis (ENS) refers to a process …

Design of nanostructures based on aromatic peptide amphiphiles

S Fleming, RV Ulijn - Chemical Society Reviews, 2014 - pubs.rsc.org
Aromatic peptide amphiphiles are gaining popularity as building blocks for the bottom-up
fabrication of nanomaterials, including gels. These materials combine the simplicity of small …

Self-assembly, bioactivity, and nanomaterials applications of peptide conjugates with bulky aromatic terminal groups

IW Hamley - ACS Applied Bio Materials, 2023 - ACS Publications
The self-assembly and structural and functional properties of peptide conjugates containing
bulky terminal aromatic substituents are reviewed with a particular focus on bioactivity …

Design strategies of stimuli-responsive supramolecular hydrogels relying on structural analyses and cell-mimicking approaches

H Shigemitsu, I Hamachi - Accounts of Chemical Research, 2017 - ACS Publications
Conspectus Stimuli-responsive hydrogels are intriguing biomaterials useful for
spatiotemporal controlled release of drugs, cells, and biological cues, cell engineering for …

Peptide π-electron conjugates: organic electronics for biology?

HAM Ardoña, JD Tovar - Bioconjugate chemistry, 2015 - ACS Publications
Highly ordered arrays of π-conjugated molecules are often viewed as a prerequisite for
effective charge-transporting materials. Studies involving these materials have traditionally …

[HTML][HTML] Hydrogels formed from Fmoc amino acids

ER Draper, KL Morris, MA Little, J Raeburn… - …, 2015 - pubs.rsc.org
A number of Fmoc amino acids can be effective low molecular weight hydrogelators. The
type of gel formed depends on the amino acid used and, in the case of FmocF, the final pH …

[HTML][HTML] Enzymatic noncovalent synthesis of supramolecular soft matter for biomedical applications

AN Shy, BJ Kim, B Xu - Matter, 2019 - cell.com
Enzymatic noncovalent synthesis (ENS), a process that integrates enzymatic reactions and
supramolecular (ie, noncovalent) interactions for spatial organization of higher-order …

Supramolecular hydrogels made of basic biological building blocks

X Du, J Zhou, B Xu - Chemistry–An Asian Journal, 2014 - Wiley Online Library
As a consequence of the self‐assembly of small organic molecules in water, supramolecular
hydrogels are evolving from serendipitous events during organic synthesis to become a new …

[HTML][HTML] MMP-9 triggered micelle-to-fibre transitions for slow release of doxorubicin

D Kalafatovic, M Nobis, N Javid, PWJM Frederix… - Biomaterials …, 2015 - pubs.rsc.org
Phenylacetyl-peptide amphiphiles were designed, which upon cleavage by a disease-
associated enzyme reconfigure from micellar aggregates to fibres. Upon this morphological …