Pharmacology and therapeutics of bronchodilators revisited
MG Matera, CP Page, L Calzetta, P Rogliani… - Pharmacological …, 2020 - Elsevier
Bronchodilators remain the cornerstone of the treatment of airway disorders such as asthma
and chronic obstructive pulmonary disease (COPD). There is therefore considerable interest …
and chronic obstructive pulmonary disease (COPD). There is therefore considerable interest …
Regulators of A20 (TNFAIP3): new drug-able targets in inflammation
G Momtazi, BN Lambrecht… - American Journal of …, 2019 - journals.physiology.org
Persistent activation of the transcription factor Nuclear factor-κB (NF-κB) is central to the
pathogenesis of many inflammatory disorders, including those of the lung such as cystic …
pathogenesis of many inflammatory disorders, including those of the lung such as cystic …
Corynebacterium tuberculostearicum, a human skin colonizer, induces the canonical nuclear factor‐κB inflammatory signaling pathway in human skin cells
MO Altonsy, HA Kurwa, GJ Lauzon… - Immunity …, 2020 - Wiley Online Library
Introduction Corynebacterium tuberculostearicum (C. t.) is a ubiquitous bacterium that
colonizes human skin. In contrast to other members of the genus Corynebacterium, such as …
colonizes human skin. In contrast to other members of the genus Corynebacterium, such as …
Effect of fracture risk in inhaled corticosteroids in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis
S Peng, C Tan, L Du, Y Niu, X Liu, R Wang - BMC Pulmonary Medicine, 2023 - Springer
Background The fracture risk of patients with chronic obstructive pulmonary disease (COPD)
treated with inhaled corticosteroids is controversial. And some large-scale randomized …
treated with inhaled corticosteroids is controversial. And some large-scale randomized …
Insights into glucocorticoid responses derived from omics studies
Glucocorticoid drugs are commonly used in the treatment of several conditions, including
autoimmune diseases, asthma and cancer. Despite their widespread use and knowledge of …
autoimmune diseases, asthma and cancer. Despite their widespread use and knowledge of …
Important lessons learned from studies on the pharmacology of glucocorticoids in human airway smooth muscle cells: Too much of a good thing may be a problem
Glucocorticoids (GCs) are the treatment of choice for chronic inflammatory diseases such as
asthma. Despite proven effective anti-inflammatory and immunosuppressive effects, long …
asthma. Despite proven effective anti-inflammatory and immunosuppressive effects, long …
Daily Eicosapentaenoic Acid Infusion in IUGR Fetal Lambs Reduced Systemic Inflammation, Increased Muscle ADRβ2 Content, and Improved Myoblast Function and …
HN Beer, TA Lacey, RL Gibbs, MS Most, ZM Hicks… - Metabolites, 2024 - mdpi.com
Intrauterine growth-restricted (IUGR) fetuses exhibit systemic inflammation that contributes to
programmed deficits in myoblast function and muscle growth. Thus, we sought to determine …
programmed deficits in myoblast function and muscle growth. Thus, we sought to determine …
[HTML][HTML] Elevated Fracture Risks in Patients Using Inhaled Corticosteroids: A Korean Nationwide Study
SH Kong, AJ Jo, CM Park, KI Park, JE Yun… - Endocrinology and …, 2024 - e-enm.org
Background In this comprehensive retrospective nationwide cohort study, we examined the
relationships between various asthma medications and bone health, utilizing data from the …
relationships between various asthma medications and bone health, utilizing data from the …
Modulation of allergic inflammation in the lung by a peptide derived from Mycobacteria tuberculosis chaperonin 60.1
Y Riffo‐Vasquez, V Kanabar, SD Keir… - Clinical & …, 2020 - Wiley Online Library
Background We have previously demonstrated that Mycobacteria tuberculosis chaperonin
60.1 inhibits leucocyte diapedesis and bronchial hyperresponsiveness in a murine model of …
60.1 inhibits leucocyte diapedesis and bronchial hyperresponsiveness in a murine model of …
TNF-α and Poly (I: C) induction of A20 and activation of NF-κB signaling are independent of ABCF1 in human airway epithelial cells
QT Cao, M Ishak, I Shpilman, JA Hirota - Scientific Reports, 2023 - nature.com
ABCF1 is the most characterized member of the ABCF family in eukaryotes with proposed
functions related to innate immunity in fibroblasts, macrophages, and epithelial cells …
functions related to innate immunity in fibroblasts, macrophages, and epithelial cells …