Yellow fever (YF) virus still represents a major threat in low resource countries in both South
America and Africa despite the presence of an effective vaccine. YF outbreaks are not only …

The flavivirus genus contains several clinically important pathogens that account for
tremendous global suffering. Primarily transmitted by mosquitos or ticks, these viruses can …

Emerging rodent-borne hantaviruses cause severe diseases in humans with no approved
vaccines or therapeutics. We recently isolated a monoclonal broadly neutralizing antibody …

We currently have an incomplete understanding of why only a fraction of human antibodies
that bind to flaviviruses block infection of cells. Here we define the footprint of a strongly …

Yellow fever virus (YFV) causes sporadic outbreaks of infection in South America and sub-
Saharan Africa. While live-attenuated yellow fever virus vaccines based on three substrains …

Flavivirus particle maturation, a process essential for virus infectivity, has been mostly
studied using dengue virus. In infected cells, immature icosahedral virions bud into the …

Background Vaccination plays a critical role in mitigating the burden associated with yellow
fever (YF). However, there is a lack of comprehensive evidence on the humoral response to …

Between 2016 and 2018, Brazil experienced major sylvatic yellow fever (YF) outbreaks that
caused hundreds of casualties, with Minas Gerais (MG) being the most affected state. These …

Yellow fever (YF) is a mosquito-borne virus infection manifested as an ailment range from
fever, headache, joint pain, body ache, epigastric pain, nausea, vomiting, exhaustion to fatal …

A febre amarela é uma doença viral aguda, que acomete seres humanos e é caracterizada
por sua gravidade e elevada taxa de mortalidade. Ela possui evolução rápida e até o …