Uridylation earmarks mRNAs for degradation… and more

H Scheer, H Zuber, C De Almeida, D Gagliardi - Trends in Genetics, 2016 - cell.com
Groundbreaking discoveries have uncovered the widespread post-transcriptional
modifications of all classes of RNA. These studies have led to the emerging notion of an …

The RNF138 E3 ligase displaces Ku to promote DNA end resection and regulate DNA repair pathway choice

IH Ismail, JP Gagné, MM Genois, H Strickfaden… - Nature cell …, 2015 - nature.com
DNA double-strand breaks (DSBs) are repaired mainly by non-homologous end joining or
homologous recombination (HR). Cell cycle stage and DNA end resection are believed to …

Systematic Analysis of Zinc Finger-Homeodomain Transcription Factors (ZF-HDs) in Barley (Hordeum vulgare L.)

MD Liu, H Liu, WY Liu, SF Ni, ZY Wang, ZH Geng… - Genes, 2024 - mdpi.com
Zinc finger-homeodomain transcription factors (ZF-HDs) are pivotal in regulating plant
growth, development, and diverse stress responses. In this study, we found 8 ZF-HD genes …

Heme promotes transcriptional and demethylase activities of Gis1, a member of the histone demethylase JMJD2/KDM4 family

S Lal, JM Comer, PC Konduri, A Shah… - Nucleic Acids …, 2018 - academic.oup.com
The yeast Gis1 protein is a transcriptional regulator belonging to the JMJD2/KDM4 subfamily
of demethylases that contain a JmjC domain, which are highly conserved from yeast to …

Mice deficient in poly (C)-binding protein 4 are susceptible to spontaneous tumors through increased expression of ZFP871 that targets p53 for degradation

W Yan, A Scoumanne, YS Jung, E Xu… - Genes & …, 2016 - genesdev.cshlp.org
Poly (C)-binding protein 4 (PCBP4), also called MCG10 and a target of p53, plays a role in
the cell cycle and is implicated in lung tumor suppression. Here, we found that PCBP4 …

[PDF][PDF] Investigating the role of 3'readenylation in facilitating 3'-5'mRNA decay in Aspergillus nidulans

N Browne-Marke - 2019 - pureportal.coventry.ac.uk
Gene expression is a multistep process where the genetic information is decoded into the
two final products, namely proteins and non-coding RNAs (ncRNAs). Gene expression …

[PDF][PDF] Biochemical Studies of Regulatory Heme-Protein Interaction and Heme Regulation in Yeast

JM Comer - 2018 - utd-ir.tdl.org
Heme is a small biomolecule produced and used by living organisms from bacteria to
humans. Heme consists of an organic porphyrin ring that coordinates an iron ion, Fe (II) or …