Molecular biology of hepatitis C virus
T Suzuki, H Aizaki, K Murakami, I Shoji… - Journal of …, 2007 - Springer
Infection with hepatitis C virus (HCV), which is distributed worldwide, often becomes
persistent, causing chronic hepatitis, cirrhosis, and hepatocellular carcinoma. For many …
persistent, causing chronic hepatitis, cirrhosis, and hepatocellular carcinoma. For many …
[HTML][HTML] Yeast-based virus-like particles as an emerging platform for vaccine development and delivery
Virus-like particles (VLPs) are empty, nanoscale structures morphologically resembling
viruses. Internal cavity, noninfectious, and particulate nature with a high density of repeating …
viruses. Internal cavity, noninfectious, and particulate nature with a high density of repeating …
[PDF][PDF] Hepatitis C virus-proteins, diagnosis, treatment and new approaches for vaccine development
H Keyvani, M Fazlalipour… - … Pacific Journal of …, 2012 - pdfs.semanticscholar.org
Abstract Background: Hepatitis C virus (HCV) causes acute and chronic human hepatitis
infection and as such is an important global health problem. The virus was discovered in the …
infection and as such is an important global health problem. The virus was discovered in the …
In vitro assembly into virus-like particles is an intrinsic quality of Pichia pastoris derived HCV core protein
N Acosta-Rivero, A Rodriguez, A Musacchio… - Biochemical and …, 2004 - Elsevier
Different variants of hepatitis C virus core protein (HCcAg) have proved to self-assemble in
vitro into virus-like particles (VLPs). However, difficulties in obtaining purified mature HCcAg …
vitro into virus-like particles (VLPs). However, difficulties in obtaining purified mature HCcAg …
Nuclear localization of nucleocapsid-like particles and HCV core protein in hepatocytes of a chronically HCV-infected patient
V Falcón, N Acosta-Rivero, G Chinea… - Biochemical and …, 2003 - Elsevier
Little is known about the life cycle of hepatitis C virus. Determination of the subcellular
localization of HCV proteins may contribute to our understanding of the in vivo functions of …
localization of HCV proteins may contribute to our understanding of the in vivo functions of …
Expression and processing of hepatitis C virus structural proteins in Pichia pastoris yeast
G Martinez-Donato, N Acosta-Rivero… - Biochemical and …, 2006 - Elsevier
Development of heterologous systems to produce useful HCV vaccine candidates is an
important part of HCV research. In this study different HCV structural region variants were …
important part of HCV research. In this study different HCV structural region variants were …
Structure and molecular virology
MJ McGarvey, M Houghton - Viral hepatitis, 2013 - Wiley Online Library
There have been major advances recently in several areas of hepatitis C virus (HCV). The
array of host receptors important for HCV entry now includes HSGP, LDLR, CD81, SRB1 …
array of host receptors important for HCV entry now includes HSGP, LDLR, CD81, SRB1 …
Signal peptide peptidase promotes the formation of hepatitis C virus non-enveloped particles and is captured on the viral membrane during assembly
N Majeau, V Gagne, M Bolduc… - Journal of general …, 2005 - microbiologyresearch.org
The maturation of the core protein (C) of Hepatitis C virus (HCV) is controlled by the signal
peptidase (sp) and signal peptide peptidase (spp) of the host. To date, it remains unknown …
peptidase (sp) and signal peptide peptidase (spp) of the host. To date, it remains unknown …
Nucleic acid binding properties and intermediates of HCV core protein multimerization in Pichia pastoris
N Acosta-Rivero, A Rodriguez, A Musacchio… - Biochemical and …, 2004 - Elsevier
Little is known about the in vivo assembly pathway or structure of the hepatitis C virus
nucleocapsid. In this work the intermediates of HCcAg multimerization in Pichia pastoris …
nucleocapsid. In this work the intermediates of HCcAg multimerization in Pichia pastoris …
Spectroscopic study of conformational changes accompanying self‐assembly of HCV core protein
A Rodríguez‐Casado, M Molina… - … Structure, Function, and …, 2007 - Wiley Online Library
Electron microscopy and infrared and Raman spectroscopy have been used here to study
the morphology, size distribution, secondary and tertiary structures of protein particles …
the morphology, size distribution, secondary and tertiary structures of protein particles …