Voltage-gated calcium channels are required for many key functions in the body. In this
review, the different subtypes of voltage-gated calcium channels are described and their …

Voltage-gated calcium (Ca2+) channels are key transducers of membrane potential
changes into intracellular Ca2+ transients that initiate many physiological events. There are …

While CaMKII has long been known to be essential for synaptic plasticity and learning,
recent work points to new dimensions of CaMKII function in the nervous system, revealing …

Excitation–transcription coupling (E–TC) links synaptic and cellular activity to nuclear gene
transcription. It is generally accepted that E–TC makes a crucial contribution to learning and …

Activity-dependent gene expression triggered by Ca 2+ entry into neurons is critical for
learning and memory, but whether specific sources of Ca 2+ act distinctly or merely supply …

L‐type calcium channels (Cav1) represent one of the three major classes (Cav1–3) of
voltage‐gated calcium channels. They were identified as the target of clinically used calcium …

TCR stimulation triggers Ca2+ signals that are critical for T cell function and immunity.
Several pore-forming α and auxiliary β subunits of voltage-gated Ca2+ channels (VGCC) …

Memory allows organisms to predict future events based on prior experiences. This requires
encoded information to persist once important predictors are extracted, while also being …

Cochlear inner hair cells (IHCs), the mammalian auditory sensory cells, encode acoustic
signals with high fidelity by Graded variations of their membrane potential trigger rapid and …

Characterizing the functional impact of novel mutations linked to autism spectrum disorder
(ASD) provides a deeper mechanistic understanding of the underlying pathophysiological …