Update on the mechanism of action of topical prostaglandins for intraocular pressure reduction
CB Toris, TG B'Ann, PL Kaufman - Survey of ophthalmology, 2008 - Elsevier
A decade has passed since the first topical prostaglandin analog was prescribed to reduce
intraocular pressure (IOP) for the treatment of glaucoma. Now four prostaglandin analogs …
intraocular pressure (IOP) for the treatment of glaucoma. Now four prostaglandin analogs …
Safety and efficacy of travoprost solution for the treatment of elevated intraocular pressure
L Quaranta, I Riva, A Katsanos, I Floriani… - Clinical …, 2015 - Taylor & Francis
Travoprost is a prostaglandin analogue widely used for reducing intraocular pressure (IOP)
in patients affected with glaucoma and ocular hypertension. It exerts its ocular hypotensive …
in patients affected with glaucoma and ocular hypertension. It exerts its ocular hypotensive …
Recreating a human trabecular meshwork outflow system on microfabricated porous structures
KY Torrejon, D Pu, M Bergkvist, J Danias… - Biotechnology and …, 2013 - Wiley Online Library
Glaucoma is the leading cause of irreversible blindness, resulting from an increase in
intraocular pressure (IOP). IOP is the only modifiable risk factor of glaucoma and is …
intraocular pressure (IOP). IOP is the only modifiable risk factor of glaucoma and is …
Preclinical challenges for developing long acting intravitreal medicines
The majority of blinding conditions arise due to chronic pathologies in the retina. During the
last two decades, antibody-based medicines administered by intravitreal injection directly …
last two decades, antibody-based medicines administered by intravitreal injection directly …
Correlation between biomechanical responses of posterior sclera and IOP elevations during micro intraocular volume change
Purpose.: This study tested the hypothesis that intraocular pressure (IOP) elevations,
induced by controlled increase of intraocular volume, are correlated with the biomechanical …
induced by controlled increase of intraocular volume, are correlated with the biomechanical …
[HTML][HTML] Pressure clamping during ocular perfusions drives nitric oxide-mediated washout
Purpose: The aim of this study was to test the hypothesis that nitric oxide (NO) mediates a
pressure-dependent, negative feedback loop that maintains conventional outflow …
pressure-dependent, negative feedback loop that maintains conventional outflow …
Effect of acute increase in blood pressure on intraocular pressure in pigs and humans
H Castejon, C Chiquet, O Savy… - … & Visual Science, 2010 - iovs.arvojournals.org
Purpose.: To study the effect on intraocular pressure (IOP) of a sudden increase in blood
pressure (BP) and of changes in partial pressure of CO 2 (pCO 2). Methods.: Two …
pressure (BP) and of changes in partial pressure of CO 2 (pCO 2). Methods.: Two …
[HTML][HTML] Effects of atorvastatin on porcine aqueous humour outflow and trabecular meshwork cells
L Cong, S Fu, J Zhang, J Zhao… - Experimental and …, 2018 - spandidos-publications.com
Primary open-angle glaucoma (POAG) with complex pathogenesis is one of the many major
causes of blindness. It is widely accepted that the major cause of POAG is the dysregulation …
causes of blindness. It is widely accepted that the major cause of POAG is the dysregulation …
[HTML][HTML] Outflow facility efficacy of five drugs in enucleated porcine eyes by a method of constant-pressure perfusion
N Li, HM Shi, L Cong, ZZ Lu, W Ye… - International Journal of …, 2015 - ncbi.nlm.nih.gov
This study aimed to characterize a technique that assesses the outflow facility (C) efficacy of
five kinds of IOP-lowering drugs commonly used clinically in enucleated porcine Eyes. Eyes …
five kinds of IOP-lowering drugs commonly used clinically in enucleated porcine Eyes. Eyes …
Bioengineered human trabecular meshwork for biological applications
M Bergkvist, S Brenner, I Danias, S Sharfstein… - US Patent …, 2016 - Google Patents
US9506907B2 - Bioengineered human trabecular meshwork for biological applications -
Google Patents US9506907B2 - Bioengineered human trabecular meshwork for biological …
Google Patents US9506907B2 - Bioengineered human trabecular meshwork for biological …